NP_000803.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,151 Da
NCBI Official Full Name
gamma-aminobutyric acid receptor subunit beta-1
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor beta1 subunit
NCBI Official Synonym Symbols
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-1
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-1
UniProt Synonym Protein Names
GABA(A) receptor subunit beta-1
NCBI Summary for GABRB1
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008]
UniProt Comments for GABRB1
GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
Protein type: Channel, chloride; Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel
Chromosomal Location of Human Ortholog: 4p12
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: GABA-A receptor activity; GABA-gated chloride ion channel activity; ligand-gated ion channel activity
Biological Process: gamma-aminobutyric acid signaling pathway; ion transport; signal transduction; transport
Disease: Epileptic Encephalopathy, Early Infantile, 45
Research Articles on GABRB1
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Pathways associated with GABRB1 elisa kit
Diseases associated with GABRB1 elisa kit
Organs/Tissues associated with GABRB1 elisa kit
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