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Camk2b recombinant protein :: Calcium/calmodulin-dependent protein kinase type II subunit beta (Camk2b) Recombinant Protein

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Catalog # MBS966917
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $970 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $1,015 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,250 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,295 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,380 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,430 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,490 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,565 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,805 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,165 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,340 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,405 +3 FREE 8GB USB
  1 mg (Yeast)  /  $2,480 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,605 +4 FREE 8GB USB
Camk2b recombinant protein
Product Name

Calcium/calmodulin-dependent protein kinase type II subunit beta (Camk2b), Recombinant Protein

Full Product Name

Recombinant Rat Calcium/calmodulin-dependent protein kinase type II subunit beta (Camk2b)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-542aa, Full length protein
Sequence
MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL KGAILTTMLA TRNFSVGRQT TAPATMSTAA SGTTMGLVEQ AKSLLNKKAD GVKPQTNSTK NSSAITSPKG SLPPAALEPQ TTVIHNPVDG IKESSDSTNT TIEDEDAKAR KQEIIKTTEQ LIEAVNNGDF EAYAKICDPG LTSFEPEALG NLVEGMDFHR FYFENLLAKN SKPIHTTILN PHVHVIGEDA ACIAYIRLTQ YIDGQGRPRT SQSEETRVWH RPDGKWQNVH FHCSGAPVAP LQ
3D Structure
ModBase 3D Structure for P08413
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rat
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Camk2b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Camk2b recombinant protein
The product of this gene belongs to the serine
threonine protein kinase family and to the Ca(2+)
calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
NCBI/Uniprot data below describe general gene information for Camk2b. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
60,402 Da
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase II beta
NCBI Official Symbol
Camk2b  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type II subunit beta
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type II subunit beta
UniProt Gene Name
Camk2b  [Similar Products]
UniProt Synonym Gene Names
CaM kinase II subunit beta; CaMK-II subunit beta  [Similar Products]
NCBI Summary for Camk2b
beta subunit of calcium/calmodulin-dependent protein kinase II; may be involved in retinal development [RGD, Feb 2006]
UniProt Comments for Camk2b
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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