NP_065700.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,396 Da
NCBI Official Full Name
chromobox protein homolog 8
NCBI Official Synonym Full Names
chromobox homolog 8
NCBI Official Synonym Symbols
NCBI Protein Information
chromobox protein homolog 8; polycomb 3; rectachrome 1; Pc class 3 homolog; chromobox homolog 8 (Pc class homolog, Drosophila)
UniProt Protein Name
Chromobox protein homolog 8
UniProt Synonym Protein Names
Polycomb 3 homolog; Pc3; hPc3; Rectachrome 1
UniProt Synonym Gene Names
UniProt Entry Name
CBX8_HUMAN
UniProt Comments for CBX8
CBX8: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Protein type: Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: nucleoplasm; heterochromatin; nuclear chromatin; PcG protein complex; nucleus
Molecular Function: protein binding; single-stranded RNA binding; ubiquitin-protein ligase activity; methylated histone residue binding
Biological Process: transcription, DNA-dependent; histone ubiquitination; negative regulation of transcription from RNA polymerase II promoter
Research Articles on CBX8
Precautions
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Products associated with CBX8 elisa kit
Pathways associated with CBX8 elisa kit
Diseases associated with CBX8 elisa kit
Organs/Tissues associated with CBX8 elisa kit
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