NP_001128471.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,675 Da
NCBI Official Full Name
fermitin family homolog 2 isoform 2
NCBI Official Synonym Full Names
fermitin family member 2
NCBI Official Synonym Symbols
MIG2; KIND2; mig-2; UNC112; PLEKHC1; UNC112B [Similar Products]
NCBI Protein Information
fermitin family homolog 2
UniProt Protein Name
Fermitin family homolog 2
UniProt Synonym Protein Names
Kindlin-2; Mitogen-inducible gene 2 protein; MIG-2; Pleckstrin homology domain-containing family C member 1; PH domain-containing family C member 1
UniProt Synonym Gene Names
KIND2; MIG2; PLEKHC1; MIG-2; PH domain-containing family C member 1 [Similar Products]
UniProt Entry Name
FERM2_HUMAN
UniProt Comments for FERMT2
Kindlin-2: Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Belongs to the kindlin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q22.1
Cellular Component: cell cortex; cell surface; cytoplasm; cytosol; extrinsic to internal side of plasma membrane; filamentous actin; focal adhesion; I band; nucleoplasm; nucleus; stress fiber
Molecular Function: phosphatidylinositol-3,4,5-triphosphate binding; protein binding
Biological Process: cell-matrix adhesion; focal adhesion formation; integrin activation; integrin-mediated signaling pathway; regulation of cell shape; transforming growth factor beta receptor signaling pathway; Wnt receptor signaling pathway
Research Articles on FERMT2
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Products associated with FERMT2 elisa kit
Pathways associated with FERMT2 elisa kit
Diseases associated with FERMT2 elisa kit
Organs/Tissues associated with FERMT2 elisa kit
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