AAF01461.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
29,377 Da
NCBI Official Full Name
guanidinoacetate N-methyltransferase
NCBI Official Synonym Full Names
guanidinoacetate N-methyltransferase
NCBI Protein Information
guanidinoacetate N-methyltransferase
UniProt Protein Name
Guanidinoacetate N-methyltransferase
NCBI Summary for GAMT
The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13. [provided by RefSeq, Feb 2012]
UniProt Comments for GAMT
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor (PubMed:26003046, PubMed:24415674, PubMed:26319512). Important in nervous system development (PubMed:24415674).
Research Articles on GAMT
Precautions
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Disclaimer
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Products associated with GAMT elisa kit
Pathways associated with GAMT elisa kit
Organs/Tissues associated with GAMT elisa kit
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