NP_001002911.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,679 Da
NCBI Official Full Name
probable G-protein coupled receptor 139 isoform 1
NCBI Official Synonym Full Names
G protein-coupled receptor 139
NCBI Official Synonym Symbols
NCBI Protein Information
probable G-protein coupled receptor 139
UniProt Protein Name
Probable G-protein coupled receptor 139
UniProt Synonym Protein Names
G(q)-coupled orphan receptor GPRg1; G-protein-coupled receptor PGR3
UniProt Synonym Gene Names
NCBI Summary for GPR139
This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
UniProt Comments for GPR139
GPR139: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 16p12.3
Cellular Component: integral component of membrane; plasma membrane
Molecular Function: neuropeptide receptor activity; protein dimerization activity
Biological Process: G-protein coupled receptor signaling pathway; neuropeptide signaling pathway; phospholipase C-activating G-protein coupled receptor signaling pathway
Research Articles on GPR139
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Organs/Tissues associated with GPR139 elisa kit
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