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CARS elisa kit :: Human cysteinyl-tRNA synthetase ELISA Kit

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Catalog # MBS9329806
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CARS elisa kit
Product Name

cysteinyl-tRNA synthetase (CARS), ELISA Kit

Popular Item
Full Product Name

Human Cysteinyl-tRNA synthetase, cytoplasmic, CARS ELISA Kit

Product Synonym Names
Human Cysteinyl-tRNA synthetase; cytoplasmic (CARS) ELISA kit; CARS1; CYSRS; MGC:11246; cysteine tRNA ligase 1; cytoplasmic; cysteine translase; cysteine-tRNA ligase; cysteinyl-tRNA synthetase
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
123859
3D Structure
ModBase 3D Structure for P49589
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Assay Type
Quantitative Sandwich
Detection Range
3.12 ng/ml - 100 ng/ml
Sensitivity
1.0 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of CARS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CARSpurchase
MBS9329806 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cysteinyl-tRNA synthetase (CARS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CARS. The ELISA analytical biochemical technique of the MBS9329806 kit is based on CARS antibody-CARS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CARS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CARS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
CARS elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CARS (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9329806. Click to request current manual
NCBI/Uniprot data below describe general gene information for CARS. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
85,473 Da
NCBI Official Full Name
cysteine--tRNA ligase, cytoplasmic isoform c
NCBI Official Synonym Full Names
cysteinyl-tRNA synthetase
NCBI Official Symbol
NCBI Official Synonym Symbols
CARS1; CYSRS; MGC:11246
  [Similar Products]
NCBI Protein Information
cysteine--tRNA ligase, cytoplasmic; cysteine translase; cysteine tRNA ligase 1, cytoplasmic
UniProt Protein Name
Cysteine--tRNA ligase, cytoplasmic
UniProt Synonym Protein Names
Cysteinyl-tRNA synthetase; CysRS
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CysRS  [Similar Products]
UniProt Entry Name
SYCC_HUMAN
NCBI Summary for CARS
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]
UniProt Comments for CARS
CARS: a class 1 aminoacyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. Two alternatively spliced isoforms are described.

Protein type: Translation; Oncoprotein; Ligase; EC 6.1.1.16

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: cytoplasm; cytosol

Molecular Function: protein binding; protein homodimerization activity; cysteine-tRNA ligase activity; metal ion binding; ATP binding; tRNA binding

Biological Process: tRNA aminoacylation for protein translation; cysteinyl-tRNA aminoacylation; gene expression
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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