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CASP9 cdna clone

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Catalog # MBS1270210
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CASP9 cdna clone
Product Name

CASP9, cDNA Clone

Popular Item
Also Known As

CASP9 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1251
Sequence
atggacgaag cggatcggcg gctcctgcgg cggtgccggc tgcggctggt ggaagagctg caggtggacc agctctggga cgccctgctg agccgcgagc tgttcaggcc ccatatgatc gaggacatcc agcgggcagg ctctggatct cggcgggatc aggccaggca gctgatcata gatctggaga ctcgagggag tcaggctctt cctttgttca tctcctgctt agaggacaca ggccaggaca tgctggcttc gtttctgcga actaacaggc aagcagcaaa gttgtcgaag ccaaccctag aaaaccttac cccagtggtg ctcagaccag agattcgcaa accagaggtt ctcagaccgg aaacacccag accagtggac attggttctg gaggatttgg tgatgtcggt gctcttgaga gtttgagggg aaatgcagat ttggcttaca tcctgagcat ggagccctgt ggccactgcc tcattatcaa caatgtgaac ttctgccgtg agtccgggct ccgcacccgc actggctcca acatcgactg tgagaagttg cggcgtcgct tctcctcgct gcatttcatg gtggaggtga agggcgacct gactgccaag aaaatggtgc tggctttgct ggagctggcg cagcaggacc acggtgctct ggactgctgc gtggtggtca ttctctctca cggctgtcag gccagccacc tgcagttccc aggggctgtc tacggcacag atggatgccc tgtgtcggtc gagaagattg tgaacatctt caatgggacc agctgcccca gcctgggagg gaagcccaag ctctttttca tccaggcctg tggtggggag cagaaagacc atgggtttga ggtggcctcc acttcccctg aagacgagtc ccctggcagt aaccccgagc cagatgccac cccgttccag gaaggtttga ggaccttcga ccagctggac gccatatcta gtttgcccac acccagtgac atctttgtgt cctactctac tttcccaggt tttgtttcct ggagggaccc caagagtggc tcctggtacg ttgagaccct ggacgacatc tttgagcagt gggctcactc tgaagacctg cagtccctcc tgcttagggt cgctaatgct gtttcggtga aagggattta taaacagatg cctggttgct ttaatttcct ccggaaaaaa cttttcttta aaacatcata a
OMIM
602234
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CASP9 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CASP9. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36,564 Da
NCBI Official Full Name
Homo sapiens caspase 9, apoptosis-related cysteine peptidase, mRNA
NCBI Official Synonym Full Names
caspase 9
NCBI Official Symbol
CASP9  [Similar Products]
NCBI Official Synonym Symbols
MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
  [Similar Products]
NCBI Protein Information
caspase-9
UniProt Protein Name
Caspase-9
UniProt Synonym Protein Names
Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3
Protein Family
UniProt Gene Name
CASP9  [Similar Products]
UniProt Synonym Gene Names
MCH6; CASP-9; APAF-3; ICE-LAP6  [Similar Products]
UniProt Entry Name
CASP9_HUMAN
NCBI Summary for CASP9
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
UniProt Comments for CASP9
CASP9: a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two isoforms.

Protein type: Protease; Apoptosis; EC 3.4.22.62

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: apoptosome; cytosol

Molecular Function: cysteine-type endopeptidase activity; enzyme activator activity; peptidase activity; protein binding; protein kinase binding; SH3 domain binding

Biological Process: apoptosis; caspase activation via cytochrome c; DNA damage response, signal transduction; DNA damage response, signal transduction resulting in induction of apoptosis; platelet formation; response to DNA damage stimulus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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