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CCL13 recombinant protein

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Catalog # MBS203685
Unit / Price
  0.01 mg  /  $310 +1 FREE 8GB USB
  0.05 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

CCL13, Recombinant Protein

Also Known As

CCL13, 24-98aa, Human, His tag, E Coli

Product Synonym Names
C-C motif chemokine 13; CKb10; MCP-4; NCC-1; NCC1; SCYA1; SCYL1; CK-beta-10; Small-inducible cytokine A13; C-C motif chemokine 13; MCP4; C-C motif chemokine 13; chemokine (C-C motif) ligand 13; ckbeta10
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
98
Sequence
MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT
OMIM
U46767 mRNA
3D Structure
ModBase 3D Structure for Q99616
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline pH7.4 containing 10% glycerol, 0.1M NaCl, 1mM DTT
Concentration
0.25 mg/ml (determined by BCA assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of CCL13 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CCL13 recombinant protein
CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha. Recombinant human CCL13 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for CCL13 recombinant protein
Applications Tested/Suitable for CCL13 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for CCL13. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10.8 kDa (96aa), confirmed by MALDI-TOF
NCBI Official Full Name
C-C motif chemokine 13
NCBI Official Synonym Full Names
C-C motif chemokine ligand 13
NCBI Official Symbol
CCL13  [Similar Products]
NCBI Official Synonym Symbols
NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13
  [Similar Products]
NCBI Protein Information
C-C motif chemokine 13
UniProt Protein Name
C-C motif chemokine 13
UniProt Synonym Protein Names
CK-beta-10; Monocyte chemoattractant protein 4; Monocyte chemotactic protein 4; MCP-4
Protein Family
UniProt Gene Name
CCL13  [Similar Products]
UniProt Synonym Gene Names
MCP4; NCC1; SCYA13; MCP-4  [Similar Products]
NCBI Summary for CCL13
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL13
Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens.
Product References and Citations for CCL13 recombinant protein
Garcia-Zepeda EA, et al.. (1996) J Immunol. 157:5613-5626

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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