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Ccl3 active protein :: C-C motif chemokine 3 protein (Ccl3) Active Protein

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Catalog # MBS969270
Unit / Price
  0.005 mg  /  $115 +1 FREE 8GB USB
  0.02 mg  /  $205 +1 FREE 8GB USB
  0.1 mg  /  $430 +1 FREE 8GB USB
  0.25 mg  /  $725 +1 FREE 8GB USB
SDS-PAGE
Product Name

C-C motif chemokine 3 protein (Ccl3), Active Protein

Popular Item
Also Known As

Recombinant Rat C-C motif chemokine 3 protein (Ccl3) (Active)

Product Synonym Names
Macrophage inflammatory protein 1-alpha; Small-inducible cytokine A3
Product Synonym Gene Name
Mip1a; Scya3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
24-92aa, Full Length of Mature Protein
Sequence Length
92
Sequence
APYGADTPTA CCFSYGRQIP RKFIADYFET SSLCSQPGVI FLTKRNRQIC ADPKETWVQE YITELELNA
3D Structure
ModBase 3D Structure for P50229
Host
E Coli
Purity/Purification
>=98% as determined by SDS-PAGE and HPLC. (lot specific)
Form/Format
Lyophilized
Species
Rattus norvegicus (Rat)
Biological Activity
Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/ml.
Storage Buffer
0.2 um filtered PBS, pH 7.4,lyophilized
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Protein Note
Protein will be provided with aseptic processing and endotoxin removal.
Preparation and Storage
Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Active Protein Note
Refer to the datasheet for activity details. For other activity applications, researchers should evaluate this protein for suitability in their model system.
Other Notes
Small volumes of Ccl3 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Ccl3 active protein
Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.

Ccl3 active protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Ccl3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7.9 kDa
NCBI Official Full Name
C-C motif chemokine 3
NCBI Official Synonym Full Names
C-C motif chemokine ligand 3
NCBI Official Symbol
NCBI Official Synonym Symbols
Scya3; MIP-1a
  [Similar Products]
NCBI Protein Information
C-C motif chemokine 3
UniProt Protein Name
C-C motif chemokine 3
UniProt Synonym Protein Names
Macrophage inflammatory protein 1-alpha; MIP-1-alpha; Small-inducible cytokine A3
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Mip1a; Scya3; MIP-1-alpha  [Similar Products]
NCBI Summary for Ccl3
mediates monocyte and neutrophil chemotaxis; may play a role in the pathogenesis of acute lung injury [RGD, Feb 2006]
UniProt Comments for Ccl3
Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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