NP_001228.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
NCBI Official Full Name
cyclin-A2
NCBI Official Synonym Full Names
cyclin A2
NCBI Official Synonym Symbols
NCBI Protein Information
cyclin-A2
UniProt Protein Name
Cyclin-A2
UniProt Synonym Gene Names
UniProt Entry Name
CCNA2_HUMAN
NCBI Summary for CCNA2
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members function as regulators of the cell cycle. This protein binds and activates cyclin-dependent kinase 2 and thus promotes transition through G1/S and G2/M. [provided by RefSeq, Aug 2016]
UniProt Comments for CCNA2
CCNA2: a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Protein type: Cell cycle regulation; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 4q27
Cellular Component: nucleoplasm; male pronucleus; cytoplasm; female pronucleus; nucleus
Molecular Function: protein binding; protein kinase binding
Biological Process: mitosis; positive regulation of fibroblast proliferation; organ regeneration; response to glucagon stimulus; cell division; positive regulation of transcription, DNA-dependent; mitotic cell cycle G2/M transition DNA damage checkpoint; regulation of G2/M transition of mitotic cell cycle; Ras protein signal transduction; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; response to estradiol stimulus
Research Articles on CCNA2
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Products associated with CCNA2 blocking peptide
Pathways associated with CCNA2 blocking peptide
Diseases associated with CCNA2 blocking peptide
Organs/Tissues associated with CCNA2 blocking peptide
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