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CD137 recombinant protein

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Catalog # MBS539375
Unit / Price
  0.02 mg  /  $310 +1 FREE 8GB USB
CD137 recombinant protein
Product Name

CD137, Recombinant Protein

Full Product Name

CD137 protein

Product Synonym Names
CD137 protein; CD-137; 4-1BB Receptor protein; TNFRSF9 protein; CD-137 protein; T-cell antigen ILA protein; CD 137; CD137; CD 137 protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
Region of CD137 protein correspond ing to amino acids MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS.
Host
Human
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Protein Type
Recombinant
Biological Significance
CD137 or 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain.
Bioactivity
Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC. About 90% of inibition was seen using a concentration of 1ug for both 4-1BBL and 4-1BBR.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
E Coli
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of CD137 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CD137 recombinant protein
Purified recombinant Human CD137 protein
Product Categories/Family for CD137 recombinant protein
Applications Tested/Suitable for CD137 recombinant protein
User optimized
NCBI/Uniprot data below describe general gene information for CD137. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
Molecular Weight
17.7 kDa
NCBI Official Full Name
CD137, partial
UniProt Protein Name
CD137
UniProt Synonym Protein Names
CD137
UniProt Gene Name
TNFRSF9  [Similar Products]
UniProt Entry Name
A9YYF3_MACFA
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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