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CD44 cdna clone

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Catalog # MBS1266130
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CD44 cdna clone
Product Name

CD44, cDNA Clone

Popular Item
Also Known As

CD44 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
2100
Sequence
atggacaagt tttggtggca cgcagcctgg ggactctgcc tcgtgccgct gagcctggcg cagatcgatt tgaatataac ctgccgcttt gcaggtgtat tccacgtgga gaaaaatggt cgctacagca tctctcggac ggaggccgct gacctctgca aggctttcaa tagcaccttg cccacaatgg cccagatgga gaaagctctg agcatcggat ttgagacctg caggtatggg ttcatagaag ggcatgtggt gattccccgg atccacccca actccatctg tgcagcaaac aacacagggg tgtacatcct cacatccaac acctcccagt atgacacata ttgcttcaat gcttcagctc cacctgaaga agattgtaca tcagtcacag acctgcccaa tgcctttgat ggaccaatta ccataactat tgttaaccgt gatggcaccc gctatgtcca gaaaggagaa tacagaacga atcctgaaga catctacccc agcaacccta ctgatgatga cgtgagcagc ggctcctcca gtgaaaggag cagcacttca ggaggttaca tcttttacac cttttctact gtacacccca tcccagacga agacagtccc tggatcaccg acagcacaga cagaatccct gctaccagta cgtcttcaaa taccatctca gcaggctggg agccaaatga agaaaatgaa gatgaaagag acagacacct cagtttttct ggatcaggca ttgatgatga tgaagatttt atctccagca ccatttcaac cacaccacgg gcttttgacc acacaaaaca gaaccaggac tggacccagt ggaacccaag ccattcaaat ccggaagtgc tacttcagac aaccacaagg atgactgatg tagacagaaa tggcaccact gcttatgaag gaaactggaa cccagaagca caccctcccc tcattcacca tgagcatcat gaggaagaag agaccccaca ttctacaagc acaatccagg caactcctag tagtacaacg gaagaaacag ctacccagaa ggaacagtgg tttggcaaca gatggcatga gggatatcgc caaacaccca gagaagactc ccattcgaca acagggacag ctgcagcctc agctcatacc agccatccaa tgcaaggaag gacaacacca agcccagagg acagttcctg gactgatttc ttcaacccaa tctcacaccc catgggacga ggtcatcaag caggaagaag gatggatatg gactccagtc atagtacaac gcttcagcct actgcaaatc caaacacagg tttggtggaa gatttggaca ggacaggacc tctttcaatg acaacgcagc agagtaattc tcagagcttc tctacatcac atgaaggctt ggaagaagat aaagaccatc caacaacttc tactctgaca tcaagcaata ggaatgatgt cacaggtgga agaagagacc caaatcattc tgaaggctca actactttac tggaaggtta tacctctcat tacccacaca cgaaggaaag caggaccttc atcccagtga cctcagctaa gactgggtcc tttggagtta ctgcagttac tgttggagat tccaactcta atgtcaatcg ttccttatca ggagaccaag acacattcca ccccagtggg gggtcccata ccactcatgg atctgaatca gatggacact cacatgggag tcaagaaggt ggagcaaaca caacctctgg tcctataagg acaccccaaa ttccagaatg gctgatcatc ttggcatccc tcttggcctt ggctttgatt cttgcagttt gcattgcagt caacagtcga agaaggtgtg ggcagaagaa aaagctagtg atcaacagtg gcaatggagc tgtggaggac agaaagccaa gtggactcaa cggagaggcc agcaagtctc aggaaatggt gcatttggtg aacaaggagt cgtcagaaac tccagaccag tttatgacag ctgatgagac aaggaacctg cagaatgtgg acatgaagat tggggtgtaa
OMIM
107269
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CD44 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CD44. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15,635 Da
NCBI Official Full Name
Homo sapiens CD44 molecule (Indian blood group), mRNA
NCBI Official Synonym Full Names
CD44 molecule (Indian blood group)
NCBI Official Symbol
NCBI Official Synonym Symbols
IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
  [Similar Products]
NCBI Protein Information
CD44 antigen
UniProt Protein Name
CD44 antigen
UniProt Synonym Protein Names
CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD_antigen: CD44
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I  [Similar Products]
UniProt Entry Name
CD44_HUMAN
NCBI Summary for CD44
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
UniProt Comments for CD44
CD44: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Interacts with PKN2. Interacts with HA, as well as other glycosaminoglycans, collagen, laminin, and fibronectin via its N-terminal segment. Interacts with ANK, the ERM proteins (VIL2, RDX and MSN), and NF2 via its C-terminal segment. Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells. 19 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cell surface; cytoplasm; focal adhesion; Golgi apparatus; plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; hyaluronic acid binding; protein binding

Biological Process: cartilage development; extracellular matrix disassembly; extracellular matrix organization and biogenesis; hyaluronan catabolic process; leukocyte migration; negative regulation of apoptosis; negative regulation of caspase activity; negative regulation of DNA damage response, signal transduction by p53 class mediator; positive regulation of heterotypic cell-cell adhesion; positive regulation of peptidyl-serine phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation

Disease: Blood Group, Indian System
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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