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Cd81 recombinant protein :: CD81 antigen Recombinant Protein

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Catalog # MBS954966
Unit / Price
  0.01 mg (E-Coli)  /  $195 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $650 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $810 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $880 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $990 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,015 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,045 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,480 +1 FREE 8GB USB
  1 mg (Yeast)  /  $1,500 +1 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,600 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $1,985 +2 FREE 8GB USB
SDS-PAGE
Product Name

CD81 antigen, Recombinant Protein

Popular Item
Also Known As

Recombinant Mouse CD81 antigen (Cd81), partial

Product Synonym Names
26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; CD81
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS954966 COA
Sequence Positions
116-201. Partial.
Sequence Length
201
Sequence
KDQIAKDV KQFYDQALQQ AVMDDDANNA KAVVKTFHET LNCCGSNALT TLTTTILRNS LCPSGGNILT PLLQQDCHQK IDELFSGK
3D Structure
ModBase 3D Structure for P35762
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Cd81 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Cd81 recombinant protein
May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

Cd81 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Cd81. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
36.8kD
NCBI Official Full Name
CD81 antigen
NCBI Official Synonym Full Names
CD81 antigen
NCBI Official Symbol
NCBI Official Synonym Symbols
Tapa1; Tapa-1; Tspan28
  [Similar Products]
NCBI Protein Information
CD81 antigen
UniProt Protein Name
CD81 antigen
UniProt Synonym Protein Names
26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; CD_antigen: CD81
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Tapa1  [Similar Products]
UniProt Entry Name
CD81_MOUSE
UniProt Comments for Cd81
CD81: May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV. Defects in CD81 are the cause of immunodeficiency common variable type 6 (CVID6); also called antibody deficiency due to CD81 defect. CVID6 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the tetraspanin (TM4SF) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: apical plasma membrane; focal adhesion; immunological synapse; integral to membrane; integral to plasma membrane; membrane; vesicle

Molecular Function: protein binding

Biological Process: activation of MAPK activity; cell surface receptor linked signal transduction; positive regulation of 1-phosphatidylinositol 4-kinase activity; positive regulation of B cell proliferation; positive regulation of cell growth; positive regulation of cell proliferation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of transcription from RNA polymerase II promoter; protein localization; receptor internalization; regulation of cell proliferation; regulation of protein stability
Product References and Citations for Cd81 recombinant protein
Genomic organization and chromosomal localization of the TAPA-1 gene.Andria M.L., Hsieh C.L., Oren R., Francke U., Levy S.J. Immunol. 147:1030-1036(1991) Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse.Paulsen M., El-Maarri O., Engemann S., Stroedicke M., Franck O., Davies K., Reinhardt R., Reik W., Walter J.Hum. Mol. Genet. 9:1829-1841(2000) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Duff K., Parsons J. Lubec G., Kang S.U.Submitted (APR-2007) to UniProtKB PGRL is a major CD81-associated protein on lymphocytes and distinguishes a new family of cell surface proteins.Clark K.L., Zeng Z., Langford A.L., Bowen S.M., Todd S.C.J. Immunol. 167:5115-5121(2001) Reduced fertility of female mice lacking CD81.Rubinstein E., Ziyyat A., Prenant M., Wrobel E., Wolf J.-P., Levy S., Le Naour F., Boucheix C.Dev. Biol. 290:351-358(2006) Expression of the mouse fragilis gene products in immune cells and association with receptor signaling complexes.Smith R.A., Young J., Weis J.J., Weis J.H.Genes Immun. 7:113-121(2006) Possible involvement of CD81 in acrosome reaction of sperm in mice.Tanigawa M., Miyamoto K., Kobayashi S., Sato M., Akutsu H., Okabe M., Mekada E., Sakakibara K., Miyado M., Umezawa A., Miyado K.Mol. Reprod. Dev. 75:150-155(2008)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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