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CDC20 cdna clone

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Catalog # MBS1273776
Unit / Price
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CDC20 cdna clone
Product Name

CDC20, cDNA Clone

Popular Item
Also Known As

CDC20 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1500
Sequence
atggcacagt tcgcgttcga gagtgacctg cactcgctgc ttcagctgga tgcacccatc cccaatgcac cccctgcgcg ctggcagcgc aaagccaagg aagccgcagg cccggccccc tcacccatgc gggccgccaa ccgatcccac agcgccggca ggactccggg ccgaactcct ggcaaatcca gttccaaggt tcagaccact cctagcaaac ctggcggtga ccgctatatc ccccatcgca gtgctgccca gatggaggtg gccagcttcc tcctgagcaa ggagaaccag cctgaaaaca gccagacgcc caccaagaag gaacatcaga aagcctgggc tttgaacctg aacggttttg atgtagagga agccaagatc cttcggctca gtggaaaacc acaaaatgcg ccagagggtt accagaacag actgaaagta ctctacagcc aaaaggccac tcctggctcc agccggaaga cctgccgtta cattccttcc ctgccagacc gtatcctgga tgcgcctgaa atccgaaatg actattacct gaaccttgtg gattggagtt ctgggaatgt actggccgtg gcactggaca acagtgtgta cctgtggagt gcaagctctg gtgacatcct gcagcttttg caaatggagc agcctgggga atatatatcc tctgtggcct ggatcaaaga gggcaactac ttggctgtgg gcaccagcag tgctgaggtg cagctatggg atgtgcagca gcagaaacgg cttcgaaata tgaccagtca ctctgcccga gtgggctccc taagctggaa cagctatatc ctgtccagtg gttcacgttc tggccacatc caccaccatg atgttcgggt agcagaacac catgtggcca cactgagtgg ccacagccag gaagtgtgtg ggctgcgctg ggccccagat ggacgacatt tggccagtgg tggtaatgat aacttggtca atgtgtggcc tagtgctcct ggagagggtg gctgggttcc tctgcagaca ttcacccagc atcaaggggc tgtcaaggcc gtagcatggt gtccctggca gtccaatgtc ctggcaacag gagggggcac cagtgatcga cacattcgca tctggaatgt gtgctctggg gcctgtctga gtgccgtgga tgcccattcc caggtgtgct ccatcctctg gtctccccat tacaaggagc tcatctcagg ccatggcttt gcacagaacc agctagttat ttggaagtac ccaaccatgg ccaaggtggc tgaactcaaa ggtcacacat cccgggtcct gagtctgacc atgagcccag atggggccac agtggcatcc gcagcagcag atgagaccct gaggctatgg cgctgttttg agttggaccc tgcgcggcgg cgggagcggg agaaggccag tgcagccaaa agcagcctca tccaccaagg catccgctga
OMIM
603618
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CDC20 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CDC20. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
54,723 Da
NCBI Official Full Name
Homo sapiens cell division cycle 20 homolog (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
cell division cycle 20
NCBI Official Symbol
CDC20  [Similar Products]
NCBI Official Synonym Symbols
CDC20A; p55CDC; bA276H19.3
  [Similar Products]
NCBI Protein Information
cell division cycle protein 20 homolog
UniProt Protein Name
Cell division cycle protein 20 homolog
UniProt Synonym Protein Names
p55CDC
UniProt Gene Name
CDC20  [Similar Products]
UniProt Entry Name
CDC20_HUMAN
NCBI Summary for CDC20
CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008]
UniProt Comments for CDC20
CDC20: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. Found in a complex with CDC20, CDC27, SPATC1 and TUBG1. Interacts with SPATC1. Interacts with NEUROD2. Interacts with MAD2L1 and BUB1B. The phosphorylated form interacts with APC/C. Interacts with NINL. May interact with MAD2L2. Interacts with CDK5RAP2. Interacts with isoform 1 of NEK2. Belongs to the WD repeat CDC20/Fizzy family.

Protein type: Ubiquitin conjugating system; Cell cycle regulation

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: anaphase-promoting complex; cytoplasm; cytosol; nucleoplasm; nucleus; spindle

Molecular Function: enzyme binding; protein binding; protein C-terminus binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; cell cycle; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of synaptic plasticity; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; sister chromatid cohesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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