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anti-CDC6 antibody :: anti-Human, Mouse CDC6 Antibody

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Catalog # MBS8509405
Unit / Price
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  0.1 mg  /  $290 +1 FREE 8GB USB
Product Name

CDC6, Antibody

Full Product Name

CDC6 (Ab-54) Antibody

Product Synonym Names
CDC18; CDC6 cell division cycle 6 homolog; CDC6-related protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q99741
Species Reactivity
Human, Mouse
CDC6 (Ab-54) antibody detects endogenous levels of total CDC6 protein.
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized non-phosphopeptide derived from human CDC6 around the phosphorylation site of serine 54 (P-L-S-P-R).
Preparation and Storage
Store at-20 degree C for 1 year
Other Notes
Small volumes of anti-CDC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CDC6 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CDC6 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:5000

Testing Data of anti-CDC6 antibody
anti-CDC6 antibody Testing Data image
Immunohistochemistry (IHC) of anti-CDC6 antibody
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using CDC6 (Ab-54) antibody. Western blot analysis of extracts from HT-29 cells, using CDC6 (Ab-54) antibody.
anti-CDC6 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CDC6. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
62,720 Da
NCBI Official Full Name
cell division control protein 6 homolog
NCBI Official Synonym Full Names
cell division cycle 6
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
cell division control protein 6 homolog
UniProt Protein Name
Cell division control protein 6 homolog
UniProt Synonym Protein Names
CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6
UniProt Gene Name
UniProt Synonym Gene Names
CDC18L; HsCdc18; HsCDC6  [Similar Products]
NCBI Summary for CDC6
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for CDC6
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Product References and Citations for anti-CDC6 antibody
Jonathan R. Hall, Mol. Biol. Cell, Jun 2007; 10.1091. Luo Feng, Mol. Biol. Cell, May 2000; 11: 1673. Arturo Calzada, J. Biol. Chem., Mar 2000; 275: 9734. Rajesh Kasiviswanathan, Nucleic Acids Res., Sep 2005; 33: 4940-4950.

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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