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CDK5R1 cdna clone

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Catalog # MBS1273267
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CDK5R1 cdna clone
Product Name

CDK5R1, cDNA Clone

Popular Item
Full Product Name

CDK5R1 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgggcacgg tgctgtccct gtctcccagc taccggaagg ccacgctgtt tgaggatggc gcggccaccg tgggccacta tacggccgta cagaacagca agaacgccaa ggacaagaac ctgaagcgcc actccatcat ctccgtgctg ccttggaaga gaatcgtggc cgtgtcggcc aagaagaaga actccaagaa ggtgcagccc aacagcagct accagaacaa catcacgcac ctcaacaatg agaacctgaa gaagtcgctg tcatgcgcca acctgtccac attcgcccag cccccaccgg cccagccgcc tgcacccccg gccagccagc tctcgggttc ccagaccggg ggctcctcct cagtcaagaa agcccctcac cctgccgtca cctccgcagg gacgcccaaa cgggtcatcg tccaggcgtc caccagtgag ctgcttcgct gcctgggtga gtttctctgc cgccggtgct accgcctgaa gcacctgtcc cccacggacc ccgtgctctg gctgcgcagc gtggaccgct cgctgcttct gcagggctgg caggaccagg gcttcatcac gccggccaac gtggtcttcc tctacatgct ctgcagggat gttatctcct ccaaggtggg ctcggatcac gagctccagg ccgtcctgct gacatgcctg tacctctcct actcctacat gggcaacgag atctcctacc cgctcaagcc cttcctggtg gagagctgca aggaggcctt ttgggaccgt tgcctctctg tcatcaacct catgagctca aagatgctgc agataaatgc cgacccacac tacttcacac aggtcttctc cgacctgaag aacgagagcg gccaggagga caagaagcgg ctcctcctag gcctggatcg gtga
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CDK5R1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CDK5R1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
Molecular Weight
34,059 Da
NCBI Official Full Name
Homo sapiens cyclin-dependent kinase 5, regulatory subunit 1 (p35), mRNA
NCBI Official Synonym Full Names
cyclin dependent kinase 5 regulatory subunit 1
NCBI Official Symbol
CDK5R1  [Similar Products]
NCBI Official Synonym Symbols
p23; p25; p35; CDK5R; NCK5A; CDK5P35; p35nck5a
  [Similar Products]
UniProt Protein Name
Cyclin-dependent kinase 5, regulatory subunit 1 (P35)
UniProt Synonym Protein Names
Cyclin-dependent kinase 5, regulatory subunit 1 (P35)
UniProt Gene Name
CDK5R1  [Similar Products]
UniProt Entry Name
Q8TAM4_HUMAN
NCBI Summary for CDK5R1
The protein encoded by this gene (p35) is a neuron-specific activator of cyclin-dependent kinase 5 (CDK5); the activation of CDK5 is required for proper development of the central nervous system. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form. The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location. The p25 form accumulates in the brain neurons of patients with Alzheimer's disease. This accumulation correlates with an increase in CDK5 kinase activity, and may lead to aberrantly phosphorylated forms of the microtubule-associated protein tau, which contributes to Alzheimer's disease. [provided by RefSeq, Jul 2008]
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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