• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CDK7 cdna clone

Scan QR to view Datasheet
Catalog # MBS1268000
Unit / Price
Scan QR to view Datasheet
  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CDK7 cdna clone
Product Name

CDK7, cDNA Clone

Popular Item
Full Product Name

CDK7 cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggctctgg acgtgaagtc tcgggcaaag cgttatgaga agctggactt ccttggggag ggacagtttg ccaccgttta caaggccaga gataagaaca ccaaccaaat tgtcgccatt aagaaaatca aacttggaca tagatcagaa gctaaagatg gtataaatag aaccgcctta agagagataa aattattaca ggagctaagt catccaaata taattggtct ccttgatgct tttggacata aatctaatat tagccttgtc tttgatttta tggaaactga tctagaggtt ataataaagg ataatagtct tgtgctgaca ccatcacaca tcaaagccta catgttgatg actcttcaag gattagaata tttacatcaa cattggatcc tacataggga tctgaaacca aacaacttgt tgctagatga aaatggagtt ctaaaactgg cagattttgg cctggccaaa tcttttggga gccccaatag agcttataca catcaggttg taaccaggtg gtatcgggcc cccgagttac tatttggagc taggatgtat ggtgtaggtg tggacatgtg ggctgttggc tgtatattag cagagttact tctaagggtt ccttttttgc caggagattc agaccttgat cagctaacaa gaatatttga aactttgggc acaccaactg aggaacagtg gccggacatg tgtagtcttc cagattatgt gacatttaag agtttccctg gaataccttt gcatcacatc ttcagtgcag caggagacga cttactagat ctcatacaag gcttattctt atttaatcca tgtgctcgaa ttacggccac acaggcactg aaaatgaagt atttcagtaa tcggccaggg ccaacacctg gatgtcagct gccaagacca aactgtccag tggaaacctt aaaggagcaa tcaaatccag ctttggcaat aaaaaggaaa agaacagagg ccttagaaca aggaggattg cccaagaaac taatttttta a
OMIM
601955
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CDK7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CDK7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,038 Da
NCBI Official Full Name
Homo sapiens cyclin-dependent kinase 7, mRNA
NCBI Official Synonym Full Names
cyclin dependent kinase 7
NCBI Official Symbol
NCBI Official Synonym Symbols
CAK; CAK1; HCAK; MO15; STK1; CDKN7; p39MO15
  [Similar Products]
NCBI Protein Information
cyclin-dependent kinase 7
UniProt Protein Name
Cyclin-dependent kinase 7
UniProt Synonym Protein Names
39 kDa protein kinase; p39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; Serine/threonine-protein kinase 1; TFIIH basal transcription factor complex kinase subunit
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CAK; CAK1; CDKN7; MO15; STK1; p39 Mo15  [Similar Products]
UniProt Entry Name
CDK7_HUMAN
NCBI Summary for CDK7
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
UniProt Comments for CDK7
CDK7: a protein kinase of the CDK family. Forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). Activates the cyclin-associated kinases CDK1, -2, -4 and -6. An essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. Serves as a direct link between the regulation of transcription and the cell cycle. Phosphorylates and activates RNA polymerase II, allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Protein type: Kinase, protein; EC 2.7.11.22; Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.23; Protein kinase, CMGC; Nuclear receptor co-regulator; CMGC group; CDK family; CDK7 subfamily; CDK/CDK7 subfamily

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: cytoplasm; holo TFIIH complex; mitochondrion; nucleoplasm; nucleus

Molecular Function: DNA-dependent ATPase activity; kinase activity; protein binding; protein C-terminus binding; protein kinase activity; protein serine/threonine kinase activity; RNA polymerase subunit kinase activity

Biological Process: cell cycle arrest; cell proliferation; G1/S transition of mitotic cell cycle; G2/M transition of mitotic cell cycle; mRNA capping; nucleotide-excision repair, preincision complex assembly; positive regulation of transcription from RNA polymerase II promoter; regulation of cyclin-dependent protein kinase activity; RNA elongation from RNA polymerase I promoter; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; termination of RNA polymerase I transcription; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase I promoter; transcription initiation from RNA polymerase II promoter; transcription-coupled nucleotide-excision repair
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000