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Cebpb recombinant protein :: CCAAT/enhancer-binding protein beta (Cebpb) Recombinant Protein

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Catalog # MBS958843
Unit / Price
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  0.05 mg (E-Coli)  /  $700 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $810 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $945 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,035 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,040 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,095 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,240 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,280 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,505 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,565 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,965 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,085 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,040 +3 FREE 8GB USB
Cebpb recombinant protein
Product Name

CCAAT/enhancer-binding protein beta (Cebpb), Recombinant Protein

Popular Item
Full Product Name

Recombinant Mouse CCAAT/enhancer-binding protein beta (Cebpb)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-296. Full length.
Sequence
MHRLLAWDAA CLPPPPAAFR PMEVANFYYE PDCLAYGAKA ARAAPRAPAA EPAIGEHERA IDFSPYLEPL APAADFAAPA PAHHDFLSDL FADDYGAKPS KKPADYGYVS LGRAGAKAAP PACFPPPPPA ALKAEPGFEP ADCKRADDAP AMAAGFPFAL RAYLGYQATP SGSSGSLSTS SSSSPPGTPS PADAKAAPAA CFAGPPAAPA KAKAKKTVDK LSDEYKMRRE RNNIAVRKSR DKAKMRNLET QHKVLELTAE NERLQKKVEQ LSRELSTLRN LFKQLPEPLL ASAGHC
3D Structure
ModBase 3D Structure for P28033
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Mouse
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Cebpb recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Cebpb recombinant protein
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
NCBI/Uniprot data below describe general gene information for Cebpb. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
15,597 Da
NCBI Official Full Name
CCAAT/enhancer-binding protein beta isoform b
NCBI Official Synonym Full Names
CCAAT/enhancer binding protein (C/EBP), beta
NCBI Official Symbol
Cebpb  [Similar Products]
NCBI Official Synonym Symbols
LAP; LIP; CRP2; NF-M; Nfil6; NF-IL6; IL-6DBP; C/EBPbeta
  [Similar Products]
NCBI Protein Information
CCAAT/enhancer-binding protein beta
UniProt Protein Name
CCAAT/enhancer-binding protein beta
UniProt Synonym Protein Names
AGP/EBP; Interleukin-6-dependent-binding protein; IL-6DBP; Liver-enriched transcriptional activator; LAP
UniProt Gene Name
Cebpb  [Similar Products]
UniProt Synonym Gene Names
C/EBP beta; IL-6DBP; LAP  [Similar Products]
UniProt Comments for Cebpb
Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:16585579, PubMed:17911624, PubMed:18486321, PubMed:20111005). Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis (PubMed:9727068, PubMed:10635333, PubMed:17301242, PubMed:17601773, PubMed:19478079, PubMed:24061474, PubMed:24216764). The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA (PubMed:15509779). Has a promitotic effect on many cell types such as hepatocytes and adipocytes but has an antiproliferative effect on T-cells by repressing MYC expression, facilitating differentiation along the T-helper 2 lineage (PubMed:9727068, PubMed:10635333, PubMed:16585579). Binds to regulatory regions of several acute-phase and cytokines genes and plays a role in the regulation of acute-phase reaction and inflammation. Plays also a role in intracellular bacteria killing (PubMed:17911624). During adipogenesis, is rapidly expressed and, after activation by phosphorylation, induces CEBPA and PPARG, which turn on the series of adipocyte genes that give rise to the adipocyte phenotype. The delayed transactivation of the CEBPA and PPARG genes by CEBPB appears necessary to allow mitotic clonal expansion and thereby progression of terminal differentiation (PubMed:15985551, PubMed:17301242, PubMed:17601773, PubMed:20194620). Essential for female reproduction because of a critical role in ovarian follicle development (PubMed:9303532). Restricts osteoclastogenesis (PubMed:19440205). Together with NFE2L1; represses expression of DSPP during odontoblast differentiation ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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