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CENTD3 peptide :: ARAP3 Peptide

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Catalog # MBS426755
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
CENTD3 peptide
Product Name

ARAP3 (CENTD3), Peptide

Also Known As

ARAP3 Immunizing Peptide

Product Synonym Names
CENTD3; centaurin, delta 3; ARAP3; FLJ21065; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; PtdIns(3,4,5)P3-binding protein; phosphoinositide binding protein; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
Product Gene Name
Product Synonym Gene Name
Antibody/Peptide Pairs
ARAP3 peptide (MBS426755) is used for blocking the activity of ARAP3 antibody (MBS421192)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
1544
Sequence
CTSSPPSSQP LT
OMIM
606647
Species Reactivity
Human, Mouse, Dog, Pig, Cow
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of CENTD3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CENTD3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
131,986 Da
NCBI Official Full Name
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
NCBI Official Synonym Full Names
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
NCBI Official Symbol
ARAP3  [Similar Products]
NCBI Official Synonym Symbols
DRAG1; CENTD3
  [Similar Products]
NCBI Protein Information
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
UniProt Protein Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
UniProt Synonym Protein Names
Centaurin-delta-3; Cnt-d3
UniProt Gene Name
ARAP3  [Similar Products]
UniProt Synonym Gene Names
CENTD3; Cnt-d3  [Similar Products]
UniProt Entry Name
ARAP3_HUMAN
NCBI Summary for CENTD3
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]
UniProt Comments for CENTD3
ARAP3: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

Protein type: Motility/polarity/chemotaxis; GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: cytoplasm; cytoskeleton; cytosol; lamellipodium; plasma membrane; ruffle

Molecular Function: GTPase activator activity; metal ion binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding

Biological Process: cytoskeleton organization and biogenesis; negative regulation of cell migration; negative regulation of Rac protein signal transduction; negative regulation of Rho protein signal transduction; positive regulation of GTPase activity; regulation of cell shape; regulation of small GTPase mediated signal transduction; signal transduction; vesicle-mediated transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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