EAW53192.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,019 Da
NCBI Official Full Name
cholinergic receptor, nicotinic, beta 2 (neuronal)
NCBI Official Synonym Full Names
cholinergic receptor nicotinic beta 2 subunit
NCBI Protein Information
neuronal acetylcholine receptor subunit beta-2
UniProt Protein Name
Neuronal acetylcholine receptor subunit beta-2
NCBI Summary for CHRNb2
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy. [provided by RefSeq, Jul 2008]
UniProt Comments for CHRNb2
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
Research Articles on CHRNb2
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Products associated with CHRNb2 antibody pair kit
Pathways associated with CHRNb2 antibody pair kit
Diseases associated with CHRNb2 antibody pair kit
Organs/Tissues associated with CHRNb2 antibody pair kit
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