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anti-CHSY1 antibody :: anti-Human, Mouse CHSY1 Antibody

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Catalog # MBS852642
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

CHSY1, Antibody

Also Known As

CHSY1 Antibody

Product Synonym Names
carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase II
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
802
OMIM
605282
3D Structure
ModBase 3D Structure for Q86X52
Species Reactivity
Human, Mouse
Specificity
CHSY1 antibody detects endogenous levels of total CHSY1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CHSY1.
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-CHSY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CHSY1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CHSY1 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000

Testing Data of anti-CHSY1 antibody
Peptide-+
anti-CHSY1 antibody Testing Data image
Immunohistochemistry (IHC) of anti-CHSY1 antibody
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CHSY1 antibody. Western blot analysis of extracts from HepG2 cells and K562 cells, using CHSY1 antibody.
anti-CHSY1 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CHSY1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
91,784 Da
NCBI Official Full Name
chondroitin sulfate synthase 1
NCBI Official Synonym Full Names
chondroitin sulfate synthase 1
NCBI Official Symbol
CHSY1  [Similar Products]
NCBI Official Synonym Symbols
CHSY; CSS1; TPBS; ChSy-1
  [Similar Products]
NCBI Protein Information
chondroitin sulfate synthase 1
UniProt Protein Name
Chondroitin sulfate synthase 1
UniProt Synonym Protein Names
Chondroitin glucuronyltransferase 1; Chondroitin synthase 1; ChSy-1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1
UniProt Gene Name
CHSY1  [Similar Products]
UniProt Synonym Gene Names
CHSY; CSS1; KIAA0990; ChSy-1  [Similar Products]
NCBI Summary for CHSY1
This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate, a glycosaminoglycan involved in many biological processes including cell proliferation and morphogenesis. Decreased expression of this gene may play a role in colorectal cancer, and mutations in this gene are a cause of temtamy preaxial brachydactyly syndrome. [provided by RefSeq, Dec 2011]
UniProt Comments for CHSY1
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Product References and Citations for anti-CHSY1 antibody
Kitagawa H., J. Biol. Chem. 276:38721-38726(2001). Nagase T., DNA Res. 6:63-70(1999). Clark H.F., Genome Res. 13:2265-2270(2003).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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