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anti-CK-19 antibody :: Rabbit Cytokeratin-19 (CK-19) Antibody

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Catalog # MBS462031
Unit / Price
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  0.1 mg  /  $285 +1 FREE 8GB USB
anti-CK-19 antibody
Product Name

Cytokeratin-19 (CK-19), Antibody

Popular Item
Full Product Name

Rabbit anti Cytokeratin-19 (CK-19) antibody

Product Synonym Names
Rabbit anti-CK-19; CK19; Keratin-19 (K19); KRT19; MGC15366; K1CS; Keratin type I 40kDa.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine
Specificity
This antibody only recognizes ~40 kDa of human Cytokeratin-19. It also reacts with mouse CK-19 protein. The other species are not tested.
Purity/Purification
The Rabbit IgG is purified by Epitope Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile phosphatebuffered saline (pH7.2) containing antibody stabilizer
Concentration
Size: 100 ug/200 ul (lot specific)
Antigen Preparation
A synthetic peptide corresponding to the C-terminus of human Cytokeratin protein.
Positive Control
MCF-7 cell lysate
Preparation and Storage
The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Other Notes
Small volumes of anti-CK-19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CK-19 antibody
Cytokeratin-19 is one member of the type A (acidic) subfamily of low molecular weight keratins. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I (A) cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
Applications Tested/Suitable for anti-CK-19 antibody
ELISA, Western Blot, Immunohistochemistry
Application Notes for anti-CK-19 antibody
Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 0.5-2 ug/ml
Molecular Weight
40 kDa
Product References and Citations for anti-CK-19 antibody
Yuan CC, et al. Cytokeratin-19 associated with apoptosis and chemosensitivity in human cervical cancer cells. Apoptosis. 1997; 2 (1):101-5.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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