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CMV antigen :: CMV-M Antigen

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Catalog # MBS318658
Unit / Price
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  1 mL  /  $490 +1 FREE 8GB USB
Testing Data
Product Name

CMV-M, Antigen

Popular Item
Full Product Name

Cytomegalovirus IgM Antigen

Product Synonym Names
Cytomegalovirus (CMV) IgM Antigen (Strain AD169) Concentrate
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Host
HF Cells
Specificity
Cytomegalovirus (CMV) IgM Antigen (Strain AD169) Concentrate
Form/Format
Partially Purified
Buffer
0.1M Glycine. pH 9.3 - 9.7
Protein Concentration
0.30-1.0mg/mL
<10% Viral Protein
Preservative
No Preservative
Dry Ice Shipment
Extra charge may be applied to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
-65 degree C or Below
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CMV antigen vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CMV antigen
Cytomegalovirus (CMV) Antigen; Viral Strain: AD169
Propagated in HF Cells
Inactivated

Introduction: Cytomegalovirus (CMV) antigen is considered one of the most common viral infections in man. The virus rarely causes disease, but may persist as a latent or chronic infection of the salivary glands, renal tubules, cervix and leukocytes. CMV infections are frequent and occasionally severe in children or adults with congenital or acquired defects of cellular immunity, such as patients with AIDS, cancer and recipients of organ transplants. The transmission of CMV via transfused blood may account for the majority of the CMV infections in organ transplant recipients, neonates and heart surgery patients. Medical conditions resulting from Cytomegalovirus infections include: interstitial pneumonia, mononucleosis (heterophile negative), congenital defects, abortion, mental retardation, blindness and deafness.

We supplies a variety of Cytomegalovirus (CMV) antigens: CMV, CMV-M, CMV-EXT 2 and our new CMV Grade III. All antigens are propagated in human fibroblast cells and infected with the viral strain, AD169. The antigen preparations are partially purified to reduce host cell components prior to inactivation by the extraction process or ultraviolet light yielding high sensitivity and low background antigens useful in a variety of solid phase immunoassays.

The various CMV antigens are designed by the extraction process to perform best in either an IgG or an IgM solid phase immunoassay but several of the antigens can be used for both IgG and IgM depending on the application.

CMV-M antigens are available at a range of concentrations: #7511 (0.3 - 0.4 mg/mL) and #7090 (~1.0mg/mL). The CMV-M antigen process extracts antigens primarily from the nucleus and endoplasmic reticulum of the infected cells to enhance the amount of antigens reacting with the early IgM antibody. In contrast, the entire cell is extracted for the #7504 CMV (0.2 - 0.3 mg/mL) antigen.

The CMV EXT2 process for #7517 is designed to select the CMV glycoprotein antigens of the infected fibroblast cells. This enriches for the antigens found on the surface of the cell that react with IgG antibodies. The new CMV Grade III antigen #7507 is purified by column chromatography to enrich for pp65 along with other CMV antigens, see the graphic below. The chromatography purified CMV Grade III has a higher specific activity after the removal of impurities and strong reactivity for both IgG and IgM sera.
Product Categories/Family for CMV antigen
Application Notes for CMV antigen
Test/ Specification/ Method/ Results
Protein Concentration/ To Report/ OD 260/ 280nm/ 1.7 mg/mL
Infectivity/ 0CPE/ Cell Culture/ Pass

Testing Data of CMV antigen
CMV antigen Testing Data image
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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