NP_077720.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,246 Da
NCBI Official Full Name
C-type natriuretic peptide
NCBI Official Synonym Full Names
natriuretic peptide C
NCBI Official Synonym Symbols
NCBI Protein Information
C-type natriuretic peptide; natriuretic peptide precursor C
UniProt Protein Name
C-type natriuretic peptide
UniProt Synonym Gene Names
UniProt Entry Name
ANFC_HUMAN
NCBI Summary for CNP
The protein encoded by this gene is proteolytically processed to form a secreted hormone of the natriuretic peptide family. The encoded hormone regulates the growth and differentiation of cartilaginous growth plate chondrocytes and may also be vasoactive and natriuretic. [provided by RefSeq, Sep 2011]
UniProt Comments for CNP
NPPC: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3. Belongs to the natriuretic peptide family.
Protein type: Secreted, signal peptide; Hormone; Secreted
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: extracellular space; secretory granule
Molecular Function: protein homodimerization activity; peptide hormone receptor binding; hormone activity; receptor binding
Biological Process: response to drug; cGMP biosynthetic process; ossification; regulation of smooth muscle cell proliferation; regulation of cAMP metabolic process; regulation of multicellular organism growth; negative regulation of meiotic cell cycle; negative regulation of DNA metabolic process; positive regulation of vasodilation; post-embryonic development; positive regulation of osteoblast differentiation; negative regulation of cell proliferation; response to ethanol; positive regulation of cGMP biosynthetic process; receptor guanylyl cyclase signaling pathway; response to hypoxia; regulation of cGMP metabolic process; regulation of blood vessel size
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Products associated with CNP elisa kit
Diseases associated with CNP elisa kit
Organs/Tissues associated with CNP elisa kit
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