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CNTFR recombinant protein

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Catalog # MBS205884
Unit / Price
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  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

CNTFR, Recombinant Protein

Popular Item
Full Product Name

CNTFR, 23-342aa, Human, His tag, E Coli (Denatured)

Product Synonym Names
Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha; CNTFR Alpha; CNTF receptor
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHHHHH SSGLVPRGSH MQRHSPQEAP HVQYERLGSD VTLPCGTANW DAAVTWRVNG TDLAPDLLNG SQLVLHGLEL GHSGLYACFH RDSWHLRHQV LLHVGLPPRE PVLSCRSNTY PKGFYCSWHL PTPTYIPNTF NVTVLHGSKI MVCEKDPALK NRCHIRYMHL FSTIKYKVSI SVSNALGHNA TAITFDEFTI VKPDPPENVV ARPVPSNPRR LEVTWQTPST WPDPESFPLK FFLRYRPLIL DQWQHVELSD GTAHTITDAY AGKEYIIQVA AKDNEIGTWS DWSVAAHATP WTEEPRHLTT EAQAAETTTS TTSSLAPPPT TKICDPGELG S
OMIM
M73238 mRNA
3D Structure
ModBase 3D Structure for P26992
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol
Concentration
1mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of CNTFR recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CNTFR recombinant protein
CNTFR also known as Ciliary neurotrophic factor receptor subunit alpha. This protein binds to CNTF. The alpha subunit provides the receptor specificity. Recombinant human CNTFR protein, was expressed in E Coli
Product Categories/Family for CNTFR recombinant protein
Applications Tested/Suitable for CNTFR recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for CNTFR. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38.1kDa (341aa)
NCBI Official Full Name
ciliary neurotrophic factor receptor subunit alpha preproprotein
NCBI Official Synonym Full Names
ciliary neurotrophic factor receptor
NCBI Official Symbol
CNTFR  [Similar Products]
NCBI Protein Information
ciliary neurotrophic factor receptor subunit alpha
UniProt Protein Name
Ciliary neurotrophic factor receptor subunit alpha
UniProt Gene Name
CNTFR  [Similar Products]
UniProt Synonym Gene Names
CNTF receptor subunit alpha; CNTFR-alpha  [Similar Products]
NCBI Summary for CNTFR
This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
UniProt Comments for CNTFR
Binds to CNTF. The alpha subunit provides the receptor specificity.
Product References and Citations for CNTFR recombinant protein
Davis S., et al. (1991). Science 253:59-63; Valenzuela D.M., et al. (1995). Genomics 25:157-163

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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