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COASY recombinant protein :: Bifunctional coenzyme A synthase (COASY) Recombinant Protein

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Catalog # MBS1345548
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $990 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $1,030 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,265 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,325 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,405 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,465 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,510 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,590 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,835 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,220 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,375 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,435 +3 FREE 8GB USB
  1 mg (Yeast)  /  $2,510 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,655 +4 FREE 8GB USB
COASY recombinant protein
Product Name

Bifunctional coenzyme A synthase (COASY), Recombinant Protein

Full Product Name

Recombinant Human Bifunctional coenzyme A synthase (COASY)

Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-564aa, full length protein
Sequence
MAVFRSGLLV LTTPLASLAP RLASILTSAA RLVNHTLYVH LQPGMSLEGP AQPQSSPVQA TFEVLDFITH LYAGADVHRH LDVRILLTNI RTKSTFLPPL PTSVQNLAHP PEVVLTDFQT LDGSQYNPVK QQLVRYATSC YSCCPRLASV LLYSDYGIGE VPVEPLDVPL PSTIRPASPV AGSPKQPVRG YYRGAVGGTF DRLHNAHKVL LSVACILAQE QLVVGVADKD LLKSKLLPEL LQPYTERVEH LSEFLVDIKP SLTFDVIPLL DPYGPAGSDP SLEFLVVSEE TYRGGMAINR FRLENDLEEL ALYQIQLLKD LRHTENEEDK VSSSSFRQRM LGNLLRPPYE RPELPTCLYV IGLTGISGSG KSSIAQRLKG LGAFVIDSDH LGHRAYAPGG PAYQPVVEAF GTDILHKDGI INRKVLGSRV FGNKKQLKIL TDIMWPIIAK LAREEMDRAV AEGKRVCVID AAVLLEAGWQ NLVHEVWTAV IPETEAVRRI VERDGLSEAA AQSRLQSQMS GQQLVEQSHV VLSTLWEPHI TQRQVEKAWA LLQKRIPKTH QALD
OMIM
609855
3D Structure
ModBase 3D Structure for Q13057
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of COASY recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for COASY. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
65,339 Da
NCBI Official Full Name
bifunctional coenzyme A synthase isoform a
NCBI Official Synonym Full Names
Coenzyme A synthase
NCBI Official Symbol
COASY  [Similar Products]
NCBI Official Synonym Symbols
NBP; DPCK; PPAT; UKR1; NBIA6; pOV-2
  [Similar Products]
NCBI Protein Information
bifunctional coenzyme A synthase
UniProt Protein Name
Bifunctional coenzyme A synthase
UniProt Synonym Protein Names
NBP; POV-2Including the following 2 domains:Phosphopantetheine adenylyltransferase (EC:2.7.7.3)Alternative name(s):Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT
UniProt Gene Name
COASY  [Similar Products]
UniProt Synonym Gene Names
CoA synthase; PPAT; DPCK; DPCOAK  [Similar Products]
NCBI Summary for COASY
Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. [provided by RefSeq, Apr 2014]
UniProt Comments for COASY
Bifunctional enzyme that catalyzes the fourth and fifth sequential steps of CoA biosynthetic pathway. The fourth reaction is catalyzed by the phosphopantetheine adenylyltransferase, coded by the coaD domain; the fifth reaction is catalyzed by the dephospho-CoA kinase, coded by the coaE domain. May act as a point of CoA biosynthesis regulation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with COASY recombinant protein
Organs/Tissues associated with COASY recombinant protein
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