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CPB1 enzyme :: Carboxypeptidase B Enzyme

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Catalog # MBS653983
Unit / Price
  5 mg  /  $375 +1 FREE 8GB USB
  10 mg  /  $525 +1 FREE 8GB USB
CPB1 enzyme
Product Name

Carboxypeptidase B (CPB1), Enzyme

Popular Item
Also Known As

Carboxypeptidase B

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS653983 COA
Chromosome Location
Chromosome: 3; NC_000003.11 (148508917..148577979). Location: 3q24
OMIM
114852
3D Structure
ModBase 3D Structure for P15086
Purity/Purification
Molecular Biology Grade
Form/Format
Chromatographically purified and supplied as a solution in 0.1M sodium chloride.
Source
Porcine Pancreas
CAS Number
9025-24-5
Activity
247 u/mg protein
3090 u/ml
12.5 mg protein/ml
Chymotrypsin
0.016%
Carboxypeptidase A
0.28%
Trypsin
0.005%
Unit Definition
1 unit hydrolyzes 1 micromole of hippuryl-L-arginine per minute at 25°C, pH 7.65
Quality Control
SDS-PAGE
Certificate of Origin
The raw animal product used in the manufacturing of Carboxypeptidase B is derived from materials originating in North America and collected in USDA approved facilities and inspected to be free of disease.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at - 20 degree C. Aliquots are stable for 6 months after receipt at -20 degree C. For maximum recovery or product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of CPB1 enzyme vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CPB1 enzyme
Carboxypeptidase B (CPB) catalyzes hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-teminal position in polypeptides. It occurs as a zymogen in the pancreas of most vertebrates.
NCBI/Uniprot data below describe general gene information for CPB1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
NCBI Official Full Name
carboxypeptidase B preproprotein
NCBI Official Synonym Full Names
carboxypeptidase B1 (tissue)
NCBI Official Symbol
NCBI Official Synonym Symbols
CPB; PASP; PCPB
  [Similar Products]
NCBI Protein Information
carboxypeptidase B; protaminase; procarboxypeptidase B; pancreas-specific protein; tissue carboxypeptidase B; pancreatic carboxypeptidase B
UniProt Protein Name
Carboxypeptidase B
UniProt Synonym Protein Names
Pancreas-specific protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
CPB; PCPB; PASP  [Similar Products]
UniProt Entry Name
CBPB1_HUMAN
NCBI Summary for CPB1
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
UniProt Comments for CPB1
Catalytic activity: Preferential release of a C-terminal lysine or arginine amino acid.

Cofactor: Binds 1 zinc ion per subunit.

Subcellular location: Secreted.

Tissue specificity: Pancreas.

Sequence similarities: Belongs to the peptidase M14 family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withCPB1 enzyme
 Reference Product  PubMed Publications
 CPE enzyme  >2 publications with CPB1 and CPE
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