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CPSF3L blocking peptide

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Catalog # MBS9218193
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  0.1 mg  /  $155 +1 FREE 8GB USB
CPSF3L blocking peptide
Product Name

CPSF3L, Blocking Peptide

Full Product Name

CPSF3L Antibody (N-term) Blocking peptide

Product Synonym Names
Integrator complex subunit 11; Int11; 3127-; Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; RC-68; CPSF3L; INTS11; RC68
Product Synonym Gene Name
INTS11; RC68[Similar Products]
Antibody/Peptide Pairs
CPSF3L peptide (MBS9218193) is used for blocking the activity of CPSF3L antibody (MBS9204630)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
611354
3D Structure
ModBase 3D Structure for Q5TA45
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Cellular Location
Nucleus. Cytoplasm
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Other Notes
Small volumes of CPSF3L blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CPSF3L blocking peptide
Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.
NCBI/Uniprot data below describe general gene information for CPSF3L. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
68,147 Da
NCBI Official Full Name
Integrator complex subunit 11
NCBI Official Synonym Full Names
cleavage and polyadenylation specific factor 3-like
NCBI Official Symbol
CPSF3L  [Similar Products]
NCBI Official Synonym Symbols
RC68; INT11; RC-68; INTS11; CPSF73L
  [Similar Products]
NCBI Protein Information
integrator complex subunit 11
UniProt Protein Name
Integrator complex subunit 11
UniProt Synonym Protein Names
Cleavage and polyadenylation-specific factor 3-like protein; CPSF3-like protein; Protein related to CPSF subunits of 68 kDa; RC-68
UniProt Gene Name
CPSF3L  [Similar Products]
UniProt Synonym Gene Names
INTS11; RC68; Int11; CPSF3-like protein; RC-68  [Similar Products]
UniProt Entry Name
INT11_HUMAN
NCBI Summary for CPSF3L
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
UniProt Comments for CPSF3L
INTS11: Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.27.-; RNA processing; Ribonuclease

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: integrator complex; nucleoplasm

Molecular Function: protein binding

Biological Process: snRNA processing; snRNA transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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