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anti-CRMP-2 antibody :: CRMP-2 Antibody

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Catalog # MBS854616
Unit / Price
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  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

CRMP-2, Antibody

Popular Item
Full Product Name

CRMP-2 (Phospho-Thr509) Antibody

Product Synonym Names
Collapsin response mediator protein 2; CRMP2; Dihydropyrimidinase related protein-2; DPYL2; DPYSL2; DRP-2; N2A3; TOAD-64; Turned on after division; 64 kDa protein; ULIP 2 protein; ULIP2
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16555
Species Reactivity
Human, Mouse, Rat
CRMP-2 (Phospho-Thr509) antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.
Affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
The antiserum was produced against synthesized phosphopeptide derived from human CRMP-2 around the phosphorylation site of threonine 509 (S-V-TP-PK).
All Sites
Human: Thr509
Mouse: Thr509
Rat: Thr509
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-CRMP-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CRMP-2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CRMP-2 antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:1000

Testing Data of anti-CRMP-2 antibody
anti-CRMP-2 antibody Testing Data image
Immunohistochemistry (IHC) of anti-CRMP-2 antibody
Immunohistochemistry analysis of paraffin-embedded human brain tissue using CRMP-2 (Phospho-Thr509) antibody. Western blot analysis of extracts from HT-29 cells, treated with heat shock, using CRMP-2 (Phospho-Thr509) antibody.
anti-CRMP-2 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CRMP-2. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
58,163 Da
NCBI Official Full Name
dihydropyrimidinase-related protein 2 isoform 1
NCBI Official Synonym Full Names
dihydropyrimidinase like 2
NCBI Official Symbol
DPYSL2  [Similar Products]
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
dihydropyrimidinase-related protein 2
UniProt Protein Name
Dihydropyrimidinase-related protein 2
UniProt Synonym Protein Names
Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2
UniProt Gene Name
DPYSL2  [Similar Products]
UniProt Synonym Gene Names
CRMP2; ULIP2; DRP-2; CRMP-2; ULIP-2  [Similar Products]
NCBI Summary for CRMP-2
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
UniProt Comments for CRMP-2
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Product References and Citations for anti-CRMP-2 antibody
Miki Y., Science 266:66-71(1994). Smith T.M., Genome Res. 6:1029-1049(1996). Wilson C.A., Oncogene 14:1-16(1997).

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Products associated with anti-CRMP-2 antibody
 Reference Product  PubMed Publications
 GSK3B antibody  >1 publications with CRMP-2 and GSK3B
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