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anti-CRP antibody :: Rabbit CRP (C-Reactive Protein) Antibody

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Catalog # MBS390098
Unit / Price
  0.5 mg  /  $485 +1 FREE 8GB USB
  1 mg  /  $780 +1 FREE 8GB USB
Testing Data)
Product Name

CRP (C-Reactive Protein), Antibody

Also Known As

Rabbit Anti-Human CRP (C-Reactive Protein) Affinity Pure

Product Synonym Names
Rabbit Anti-Human C-Reactive Protein (CRP), Polyclonal Antibody; Affinity Purified
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
238
3D Structure
ModBase 3D Structure for Q07203
Host
Rabbit
Specificity
Specifically binds to human CRP. Dilution for immunoblot and ELISA range: 200 to 160,000.
Concentration
1 mg / ml (OD 1.35 / 280 nm). (lot specific)
Source Note
Polyclonal antibody purified by human CRP-Sepharose affinity column.*
Preservative
75 mM PBS, 75 mM NaCl, 0.02% NaN3, 0.5 mM EDTA, pH 7.2.
Preparation and Storage
-20 degree C for long-term storage, 2-8 degree C for short-term storage. Aliquot to avoid repeated thaw and freeze.
Other Notes
Small volumes of anti-CRP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CRP antibody
Human C-reactive protein (CRP) is an acute phase protein produced by the liver. It is a member of the pentraxin family of proteins with five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa). Among other markers of inflammation, CRP has been showed the strongest association with cardiovascular events. Clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. It is an important biomarker for detecting individuals at high risk of plaque rapture.
Product Categories/Family for anti-CRP antibody
Applications Tested/Suitable for anti-CRP antibody
ELISA (EIA), Immunoblot (IB)
Application Notes for anti-CRP antibody
Dilution for Immunoblot & ELISA range: 1,000 to 160,000.
Use: The antibody can be used for detection of CRP in plasma and lipoproteins, immunoassays, immunoblots, enzyme conjugation, or biotinylation.

Testing Data) of anti-CRP antibody
anti-CRP antibody Testing Data) image
NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
27,085 Da
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related, gene 4<
NCBI Official Symbol
crp.4-a  [Similar Products]
NCBI Official Synonym Symbols
CRP; ptx1; crp.4a
  [Similar Products]
NCBI Protein Information
C-reactive protein; C-reactive protein, pentraxin-related, gene 4 a
UniProt Protein Name
C-reactive protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CRP_XENLA
UniProt Comments for CRP
Function: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.

Cofactor: Binds 2 calcium ions per subunit

By similarity.

Subunit structure: Homodimer; disulfide-linked. It is not known if it assembles into a pentaxin (or pentraxin) structure. Pentaxins have a discoid arrangement of 5 non-covalently bound subunits.

Subcellular location: Secreted.

Developmental stage: Is initially detected at the late tail bud stage when the liver appears. Ref.1

Post-translational modification: Cys-89 or Cys-223 or Cys-236 could be involved in interchain disulfide linkage.

Sequence similarities: Belongs to the pentaxin family.Contains 1 pentaxin domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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