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CRP protein :: C-Reactive Protein

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Catalog # MBS173367
Unit / Price
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  1 mg  /  $200 +1 FREE 8GB USB
  10 mg  /  $880 +1 FREE 8GB USB
  25 mg  /  $1,680 +2 FREE 8GB USB
CRP protein
Product Name

C-Reactive (CRP), Protein

Popular Item
Full Product Name

C-Reactive Protein (CRP), Human Pleural Fluid

Product Synonym Names
CRP; C-Reactive Protein (CRP), Human - >=99% (SDS-PAGE) - Lyophilized
Product Gene Name
Product Synonym Gene Name
RP11-419N10.4; PTX1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
MBS173367 COA
MBS173367 MSDS
OMIM
123260
3D Structure
ModBase 3D Structure for P02741
Host
Human Pleural Fluid
Purity/Purification
>= 99% (SDS-PAGE)
Form/Format
Lyophilized from sodium citrate pH 6.5 with polyethylene glycol and trehalose
CAS Number
9007-41-4
Appearance
White to off-white powder.
Solubility
Clear, Colorless (1mg protein/mL tris buffered saline with 5mM calcium chloride, pH 8.0)
Protein
0.13 mg protein/mg solid (E0.1%280 nm=1.8)
Handling
Handle as a potentially hazardous substance.
Preparation and Storage
Store at 2-8°C
Storage Note: Protect from moisture.
Shipping Note: Cold pack.
Other Notes
Small volumes of CRP protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CRP protein
MyBioSource is a major supplier of C-Reactive Protein (CRP) for medical research and diagnostic manufacturing. C-Reactive Protein is purified using multiple affinity chromotagraphy steps.

Custom preparations, technical support, bulk quantities and aliquoting available.

C-Reactive Protein (CRP) is a pentameric serum protein belonging to the pentraxin family that is comprised of five identical ~ 23kDa subunits. CRP is a positive acute phase reactant, the levels of which increase modestly in humans in response to inflammation, tissue injury or disease. The acute phase response develops in a wide range of acute and chronic inflammatory conditions like bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury or necrosis.
NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
118,000
NCBI Official Full Name
C-reactive protein
NCBI Official Synonym Full Names
C-reactive protein, pentraxin-related
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
C-reactive protein; pentraxin 1
UniProt Protein Name
C-reactive protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CRP_HUMAN
NCBI Summary for CRP
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
UniProt Comments for CRP
CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; virion binding; low-density lipoprotein binding; calcium ion binding

Biological Process: protein polymerization; wound healing; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with CRP protein
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