NP_060841.5
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,917 Da
NCBI Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Official Synonym Full Names
chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Official Synonym Symbols
ChGn; CSGalNAcT-1; beta4GalNAcT [Similar Products]
NCBI Protein Information
chondroitin sulfate N-acetylgalactosaminyltransferase 1; beta4GalNAcT-1; chondroitin beta1,4 N-acetylgalactosaminyltransferase; chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1
UniProt Protein Name
Chondroitin sulfate N-acetylgalactosaminyltransferase 1
UniProt Synonym Protein Names
Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1
UniProt Synonym Gene Names
UniProt Entry Name
CGAT1_HUMAN
UniProt Comments for CS
ChGn: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174; Transferase
Chromosomal Location of Human Ortholog: 8p21.3
Cellular Component: Golgi membrane; integral to Golgi membrane; intracellular
Molecular Function: glucuronosyltransferase activity; metal ion binding; acetylgalactosaminyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; peptidoglycan glycosyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity
Biological Process: nervous system development; anatomical structure morphogenesis; extracellular matrix organization and biogenesis; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; chondroitin sulfate proteoglycan biosynthetic process; cell recognition; pathogenesis; UDP-N-acetylgalactosamine metabolic process; chondroitin sulfate metabolic process; cell proliferation; UDP-glucuronate metabolic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparin biosynthetic process; proteoglycan biosynthetic process; cartilage development; carbohydrate metabolic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; endochondral ossification
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Pathways associated with CS elisa kit
Organs/Tissues associated with CS elisa kit
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