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CSF2RB recombinant protein :: Cytokine receptor common subunit beta Recombinant Protein

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Catalog # MBS206148
Unit / Price
  0.05 mg  /  $310 +1 FREE 8GB USB
  0.25 mg  /  $925 +1 FREE 8GB USB
SDS-Page
Product Name

Cytokine receptor common subunit beta (CSF2RB), Recombinant Protein

Popular Item
Also Known As

Cytokine receptor common subunit beta, 17-443aa, Human, His tag, Baculovirus

Product Synonym Names
CD131; CDw131; IL3RB; IL5RB; SMDP5; CSF2RB
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
897
Sequence
WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH
OMIM
M59941 mRNA
3D Structure
ModBase 3D Structure for P32927
Host
Baculovirus
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (lot specific)
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of CSF2RB recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CSF2RB recombinant protein
CSF2RB, also known as cytokine receptor common subunit beta, is a high affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. This unusual form of receptor assembly likely applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their mechanism of activation and for the development of therapeutics. Recombinant human CSF2RB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for CSF2RB recombinant protein
Applications Tested/Suitable for CSF2RB recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for CSF2RB. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49.7kDa (435aa) 40-57kDa (SDS-PAGE under reducing conditions)[Similar Products]
NCBI Official Full Name
cytokine receptor common subunit beta
NCBI Official Synonym Full Names
colony stimulating factor 2 receptor beta common subunit
NCBI Official Symbol
CSF2RB  [Similar Products]
NCBI Official Synonym Symbols
CD131; IL3RB; IL5RB; SMDP5; CDw131; betaGMR
  [Similar Products]
NCBI Protein Information
cytokine receptor common subunit beta
UniProt Protein Name
Cytokine receptor common subunit beta
UniProt Synonym Protein Names
CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131
Protein Family
UniProt Gene Name
CSF2RB  [Similar Products]
UniProt Synonym Gene Names
IL3RB; IL5RB  [Similar Products]
NCBI Summary for CSF2RB
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
UniProt Comments for CSF2RB
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Product References and Citations for CSF2RB recombinant protein
Hansen G., et al. (2008) Cell. 134:496-507.; Mulhern TD., et al. (2000) J Mol Biol. 297:989-1001.

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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