NP_001311.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
24,942 Da
NCBI Official Full Name
casein kinase II subunit beta isoform 1
NCBI Official Synonym Full Names
casein kinase 2, beta polypeptide
NCBI Protein Information
casein kinase II subunit beta; phosvitin; CK II beta; protein G5a; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; Casein kinase II beta subunit; alternative name: G5a, phosvitin; chimera CSNK2B-LY6G5B splicing isoform 532; chimera CSNK2B-LY6G5B splicing isoform 560; casein kinase II b subunit splicing isoform 318; casein kinase II b subunit splicing isoform 660; casein kinase II b subunit splicing isoform 806
UniProt Protein Name
Casein kinase II subunit beta
UniProt Synonym Protein Names
Phosvitin; Protein G5a
UniProt Synonym Gene Names
UniProt Entry Name
CSK2B_HUMAN
NCBI Summary for CSN2
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
UniProt Comments for CSN2
CK2B: a regulatory subunit of the casein kinase 2 holoenzyme. Exists as a tetramer composed of two catalytic subunits, alpha and alpha-prime, and two regulatory beta subunits. The beta subunits undergo autophosphorylation. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Participates in Wnt signaling
Protein type: Protein kinase, regulatory subunit
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: cytoplasm; plasma membrane; protein kinase CK2 complex; PcG protein complex; nucleus; cytosol
Molecular Function: identical protein binding; protein domain specific binding; protein serine/threonine kinase activity; protein binding; metal ion binding; protein kinase regulator activity; transcription factor binding; receptor binding
Biological Process: negative regulation of cell proliferation; axon guidance; positive regulation of activin receptor signaling pathway; cellular protein complex assembly; Wnt receptor signaling pathway; regulation of DNA binding; adiponectin-mediated signaling pathway; mitotic cell cycle; negative regulation of blood vessel endothelial cell migration; signal transduction; regulation of protein kinase activity; protein amino acid phosphorylation
Research Articles on CSN2
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Products associated with CSN2 elisa kit
Pathways associated with CSN2 elisa kit
Diseases associated with CSN2 elisa kit
Organs/Tissues associated with CSN2 elisa kit
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