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cTnT protein :: Troponin T Cardiac Protein

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Catalog # MBS664015
Unit / Price
  0.1 mg  /  $1,940 +2 FREE 8GB USB
  0.5 mg  /  $3,730 +4 FREE 8GB USB
  1 mg  /  $5,285 +6 FREE 8GB USB
cTnT protein
Product Name

Troponin T Cardiac (cTnT), Protein

Also Known As

Rabbit cardiac troponin T (cTnT)

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
299
Form/Format
Lyophilized from 0.01 M HCl.
Product is recommended to reconstitute with urea/Tris buffer, pH 7.5 (7 M urea, 5 mM EDTA, 15 mM mercaptoethanol, 20 mM Tris).
Source Note
Rabbit heart tissue.
Analysis
Purity > 98 % (SDS-PAGE).
Immunological identity confirmed by reaction with monoclonal antibody that is specific for the TnT cardiac isoform.
Preparation and Storage
At -20 degree C (-70 degree C for long term storage)
Other Notes
Small volumes of cTnT protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for cTnT. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Related Accession #
Molecular Weight
34,452 Da
NCBI Official Full Name
troponin T, cardiac muscle
NCBI Official Synonym Full Names
troponin T type 2 (cardiac)
NCBI Official Symbol
Tnnt2  [Similar Products]
NCBI Official Synonym Symbols
Ctt; CTTG; Tnnt3; RATCTTG
  [Similar Products]
NCBI Protein Information
troponin T, cardiac muscle; cTnT; tnTc; Troponin T cardiac; cardiac troponin T2; troponin T2, cardiac; cardiac muscle troponin T
UniProt Protein Name
Troponin T, cardiac muscle
UniProt Synonym Protein Names
Cardiac muscle troponin T; cTnT
UniProt Gene Name
Tnnt2  [Similar Products]
UniProt Synonym Gene Names
TnTc; cTnT  [Similar Products]
UniProt Entry Name
TNNT2_RAT
NCBI Summary for cTnT
tropomyosin-binding subunit of troponin; confers calcium-sensitivy to actinomysin ATPase activity in striated muscle [RGD, Feb 2006]
UniProt Comments for cTnT
TNNT2: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart. Belongs to the troponin T family. 11 isoforms of the human protein are produced by alternative splicing.

Protein type: Motor; Motility/polarity/chemotaxis

Cellular Component: sarcomere; troponin complex; myofibril; cytoplasm; striated muscle thin filament

Molecular Function: protein binding, bridging; troponin C binding; structural constituent of cytoskeleton; troponin I binding; ATPase activity; tropomyosin binding; actin binding

Biological Process: actin crosslink formation; protein heterooligomerization; atrial cardiac muscle morphogenesis; metabolic process; regulation of muscle contraction; heart development; regulation of muscle filament sliding speed; sarcomere organization; regulation of heart contraction; muscle filament sliding; muscle contraction; positive regulation of ATPase activity; ventricular cardiac muscle morphogenesis; response to calcium ion; negative regulation of ATPase activity; cardiac muscle contraction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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