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CTSG native protein :: Cathepsin G Native Protein

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Catalog # MBS318181
Unit / Price
  0.1 mg  /  $430 +1 FREE 8GB USB
CTSG native protein
Product Name

Cathepsin G (CTSG), Native Protein

Popular Item
Also Known As

Human Cathepsin G

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
Chromosome Location
Chromosome: 14; NC_000014.8 (25042724..25045466, complement). Location: 14q11.2
3D Structure
ModBase 3D Structure for P08311
Human Neutrophil
Cathepsin G
>95% pure (SDS-PAGE)
Purified, Lyophilized
We suggest using 50mM Na Acetate, pH 5.5, with 150mM Sodium Chloride as the buffer to be added to the salt-free lyophilized solid.
Not applicable
Activity: 2 to 4 Units/mg protein. One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-ala-ala-pro-phe-pNA (1mM) per minute at 25 degree C in 160mM Tris-HCl, pH 7.4 containing 1.6M Sodium chloride (lot specific)
Not applicable.
Not applicable
All human source materials have tested negative for HIV 1, HIV 2 and non-reactive for anti-HCV, HBsAg and anti-HBc. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be conside
Preparation and Storage
Store at -20 degree C. Avoid multiple freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CTSG native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for CTSG native protein
NCBI/Uniprot data below describe general gene information for CTSG. It may not necessarily be applicable to this product.
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,837 Da[Similar Products]
NCBI Official Full Name
cathepsin G
NCBI Official Synonym Full Names
cathepsin G
NCBI Official Symbol
NCBI Official Synonym Symbols
CG; CATG; MGC23078
  [Similar Products]
NCBI Protein Information
cathepsin G; OTTHUMP00000178752
UniProt Protein Name
Cathepsin G
Protein Family
UniProt Gene Name
UniProt Entry Name
NCBI Summary for CTSG
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq]
UniProt Comments for CTSG
Function: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. Ref.6 Ref.9 Ref.11

Catalytic activity: Specificity similar to chymotrypsin C.

Enzyme regulation: Inhibited by soybean trypsin inhibitor, benzamidine, the synthetic peptide R13K, Z-Gly-Leu-Phe-CH2Cl, phenylmethylsulfonyl fluoride, 3,4-dichloroisocoumarin, DFP, SBTI and alpha-1-antitrypsin. Inhibited by LPS from P.aeruginosa but not by LPS from S.minnesota. Not inhibited by elastinal, CMK, TLCK and ETDA. Ref.6 Ref.9 Ref.11

Subcellular location: Cell surface Ref.6.

Sequence similarities: Belongs to the peptidase S1 family.Contains 1 peptidase S1 domain.

Biophysicochemical propertiesKinetic parameters:KM=1.15 mM for Z-Lys-SBzl Ref.6KM=0.26 mM for Suc-Ala-Ala-Pro-Phe-SBzl
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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