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Cxcl16 recombinant protein :: C-X-C motif chemokine 16 Recombinant Protein

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Catalog # MBS717391
Unit / Price
Scan QR to view Datasheet
  0.01 mg  /  $200 +1 FREE 8GB USB
  0.05 mg  /  $260 +1 FREE 8GB USB
  0.1 mg  /  $430 +1 FREE 8GB USB
  0.2 mg  /  $685 +1 FREE 8GB USB
  0.5 mg  /  $1,125 +1 FREE 8GB USB
  1 mg  /  $1,725 +2 FREE 8GB USB
SDS-PAGE
Product Name

C-X-C motif chemokine 16 (Cxcl16), Recombinant Protein

Full Product Name

Recombinant Mouse C-X-C motif chemokine 16 protein

Product Synonym Names
Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-198aa; Partial
Sequence
NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLPQA STQTPEAAEG TPSDTSTPAH SQSTQHSTLP SGALSLNKEH TQPWEMTTLP SGYGLEARPE AEANEKQQDD RQQEAPGAGA ST
3D Structure
ModBase 3D Structure for Q8BSU2
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE. (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of Cxcl16 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Cxcl16 recombinant protein
Induces a strong chotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.

Cxcl16 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for Cxcl16. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22.8kD
NCBI Official Full Name
C-X-C motif chemokine 16
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 16
NCBI Official Symbol
Cxcl16  [Similar Products]
NCBI Official Synonym Symbols
SR-PSOX; Zmynd15; AV290116; BB024863; CXCL16v1; CXCL16v2; b2b498Clo; 0910001K24Rik
  [Similar Products]
NCBI Protein Information
C-X-C motif chemokine 16
UniProt Protein Name
C-X-C motif chemokine 16
UniProt Synonym Protein Names
Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
Protein Family
UniProt Gene Name
Cxcl16  [Similar Products]
UniProt Synonym Gene Names
Srpsox; SR-PSOX  [Similar Products]
UniProt Entry Name
CXL16_MOUSE
UniProt Comments for Cxcl16
CXCL16: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Membrane protein, integral

Cellular Component: extracellular space; integral to membrane; membrane

Molecular Function: chemokine activity; chemokine receptor binding; cytokine activity; low-density lipoprotein receptor activity; scavenger receptor activity

Biological Process: chemotaxis; lymphocyte chemotaxis; positive regulation of cell growth; positive regulation of cell migration; receptor-mediated endocytosis; response to cytokine stimulus
Product References and Citations for Cxcl16 recombinant protein
A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Matloubian M., David A., Engel S., Ryan J.E., Cyster J.G.Nat. Immunol. 1:298-304(2000) Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages.Shimaoka T., Kume N., Minami M., Hayashida K., Kataoka H., Kita T., Yonehara S.J. Biol. Chem. 275:40663-40666(2000) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.PLoS Biol. 7:E1000112-E1000112(2009) Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.Yan W., Si Y., Slaymaker S., Li J., Zheng H., Young D.L., Aslanian A., Saunders L., Verdin E., Charo I.F.J. Biol. Chem. 285:31418-31426(2010)

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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