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CXCR7 elisa kit :: Rat Chemokine C-X-C-Motif Receptor 7 ELISA Kit

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Catalog # MBS059206
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CXCR7 elisa kit
Product Name

Chemokine C-X-C-Motif Receptor 7 (CXCR7), ELISA Kit

Popular Item
Full Product Name

Rat Chemokine C-X-C-Motif Receptor 7 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
146928
3D Structure
ModBase 3D Structure for P25025
Species Reactivity
Samples
Serum, Plasma and Tissue Homogenate
Assay Type
Sandwich
Detection Range
0.25 ng/ml - 8 ng/ml.
Sensitivity
0.1 ng/ml.
Intended Uses
This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CXCR7 (hereafter termed this analyte) in Rat serum, plasma and tissue homogenate samples.
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of CXCR7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CXCR7purchase
MBS059206 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemokine C-X-C-Motif Receptor 7 (CXCR7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCR7. The ELISA analytical biochemical technique of the MBS059206 kit is based on CXCR7 antibody-CXCR7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCR7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCR7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
CXCR7 elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CXCR7 (hereafter termed this analyte) in Rat serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS059206. Click to request current manual
NCBI/Uniprot data below describe general gene information for CXCR7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
40,759 Da
NCBI Official Full Name
C-X-C chemokine receptor type 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 2
NCBI Official Symbol
CXCR2  [Similar Products]
NCBI Official Synonym Symbols
CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b
  [Similar Products]
NCBI Protein Information
C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B
UniProt Protein Name
C-X-C chemokine receptor type 2
UniProt Synonym Protein Names
CDw128b; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2
UniProt Gene Name
CXCR2  [Similar Products]
UniProt Synonym Gene Names
IL8RB; CXC-R2; CXCR-2; IL-8R B  [Similar Products]
UniProt Entry Name
CXCR2_HUMAN
NCBI Summary for CXCR7
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
UniProt Comments for CXCR7
IL-8R B: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Receptor, cytokine; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: mast cell granule; cell surface; membrane; integral to plasma membrane; plasma membrane; intracellular

Molecular Function: signal transducer activity; protein binding; interleukin-8 receptor activity; interleukin-8 binding; C-X-C chemokine receptor activity

Biological Process: neutrophil chemotaxis; neutrophil activation; signal transduction; chemotaxis; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; positive regulation of angiogenesis; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; receptor internalization; midbrain development; positive regulation of cell proliferation; cellular defense response; dendritic cell chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; acute inflammatory response to antigenic stimulus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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