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CYB5A cdna clone

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Catalog # MBS1271589
Unit / Price
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  0.01 mg Plasmid + 0.2 mL Glycerol-Stock  /  $165 +1 FREE 8GB USB
CYB5A cdna clone
Product Name

CYB5A, cDNA Clone

Popular Item
Full Product Name

CYB5A cDNA Clone

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcagagc agtcggacga ggccgtgaag tactacaccc tagaggagat tcagaagcac aaccacagca agagcacctg gctgatcctg caccacaagg tgtacgattt gaccaaattt ctggaagagc atcctggtgg ggaagaagtt ttaagggaac aagctggagg tgacgctact gagaactttg aggatgtcgg gcactctaca gatgccaggg aaatgtccaa aacattcatc attggggagc tccatccaga tgacagacca aagttaaaca agcctccgga aactcttatc actactattg attctagttc cagttggtgg accaactggg tgatccctgc catctctgca gtggccgtcg ccttgatgta tcgcctatac atggcagagg actga
OMIM
250790
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CYB5A cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CYB5A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,169 Da
NCBI Official Full Name
Homo sapiens cytochrome b5 type A (microsomal), mRNA
NCBI Official Synonym Full Names
cytochrome b5 type A
NCBI Official Symbol
CYB5A  [Similar Products]
NCBI Official Synonym Symbols
CYB5; MCB5
  [Similar Products]
NCBI Protein Information
cytochrome b5
UniProt Protein Name
Cytochrome b5
UniProt Synonym Protein Names
Microsomal cytochrome b5 type A; MCB5
Protein Family
UniProt Gene Name
CYB5A  [Similar Products]
UniProt Synonym Gene Names
CYB5; MCB5  [Similar Products]
UniProt Entry Name
CYB5_HUMAN
NCBI Summary for CYB5A
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
UniProt Comments for CYB5A
CYB5A: Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A). A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. Belongs to the cytochrome b5 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Oxidoreductase; Endoplasmic reticulum; Mitochondrial

Chromosomal Location of Human Ortholog: 18q23

Cellular Component: cytoplasm; intracellular membrane-bound organelle; membrane; mitochondrial outer membrane

Molecular Function: aldo-keto reductase activity; cytochrome-c oxidase activity; enzyme binding

Biological Process: L-ascorbic acid metabolic process

Disease: Methemoglobinemia Type Iv
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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