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CYP19A1 elisa kit :: Human Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA Kit

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Catalog # MBS035985
Unit / Price
  48-Strip-Wells  /  $470 +1 FREE 8GB USB
  96-Strip-Wells  /  $680 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
  10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
Typical Testing Data/Standard Curve (for reference only)
Product Name

Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1), ELISA Kit

Popular Item
Full Product Name

Human Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Chromosome Location
Chromosome: 15; NC_000015.9 (51500254..51630795, complement). Location: 15q21.1
OMIM
107910
3D Structure
ModBase 3D Structure for P11511
Species Reactivity
Samples
Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
Detection Range
0.625 ng/ml ~ 20 ng/ml.
Sensitivity
0.1 ng/ml.
Intended Uses
This ELISA kit is intended for laboratory in vitro research use only, not for drug, household or other use! The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm by a spectrophotometer. In order to measure the concentration of Human CYP19A1 in the sample, this ELISA kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus Human CYP19A1 concentration. The concentration of Human CYP19A1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
Intra-assay Precision
Intra-assay CV (%) are less than 15%.
Inter-assay Precision
Inter-assay CV (%) are less than 15%.
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of CYP19A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forCYP19A1purchase
MBS035985 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 (CYP19A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYP19A1. The ELISA analytical biochemical technique of the MBS035985 kit is based on CYP19A1 antibody-CYP19A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP19A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP19A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Typical Testing Data/Standard Curve (for reference only) of CYP19A1 elisa kit
CYP19A1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Sample Manual Insert of MBS035985. Click to request current manual
NCBI/Uniprot data below describe general gene information for CYP19A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,883 Da
NCBI Official Full Name
cytochrome P450 19A1
NCBI Official Synonym Full Names
cytochrome P450, family 19, subfamily A, polypeptide 1
NCBI Official Symbol
CYP19A1  [Similar Products]
NCBI Official Synonym Symbols
ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
  [Similar Products]
NCBI Protein Information
cytochrome P450 19A1; aromatase; estrogen synthase; estrogen synthetase; cytochrome P-450AROM; microsomal monooxygenase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily XIX (aromatization of androgens)
UniProt Protein Name
Cytochrome P450 19A1
UniProt Synonym Protein Names
Aromatase; CYPXIX; Cytochrome P-450AROM; Estrogen synthase
Protein Family
UniProt Gene Name
CYP19A1  [Similar Products]
UniProt Synonym Gene Names
ARO1; CYAR; CYP19  [Similar Products]
UniProt Entry Name
CP19A_HUMAN
NCBI Summary for CYP19A1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
UniProt Comments for CYP19A1
CYP19A1: Catalyzes the formation of aromatic C18 estrogens from C19 androgens. Belongs to the cytochrome P450 family.

Protein type: Lipid Metabolism - androgen and estrogen; EC 1.14.14.14; Oxidoreductase

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum

Molecular Function: electron carrier activity; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; oxygen binding

Biological Process: steroid metabolic process; xenobiotic metabolic process; androgen metabolic process; steroid biosynthetic process; estrogen biosynthetic process; sterol metabolic process

Disease: Aromatase Deficiency; Aromatase Excess Syndrome
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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