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CYP2C8 recombinant protein :: Cytochrome P450 2C8 (CYP2C8) Recombinant Protein

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Catalog # MBS949831
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $885 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $975 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,185 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,305 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,310 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,425 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,480 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,710 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $1,975 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,220 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,305 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,340 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,425 +4 FREE 8GB USB
CYP2C8 recombinant protein
Product Name

Cytochrome P450 2C8 (CYP2C8), Recombinant Protein

Full Product Name

Recombinant Human Cytochrome P450 2C8 (CYP2C8)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
27-490. Full Length of Mature Protein
Sequence
RKLPPGPTPL PIIGNMLQID VKDICKSFTN FSKVYGPVFT VYFGMNPIVV FHGYEAVKEA LIDNGEEFSG RGNSPISQRI TKGLGIISSN GKRWKEIRRF SLTTLRNFGM GKRSIEDRVQ EEAHCLVEEL RKTKASPCDP TFILGCAPCN VICSVVFQKR FDYKDQNFLT LMKRFNENFR ILNSPWIQVC NNFPLLIDCF PGTHNKVLKN VALTRSYIRE KVKEHQASLD VNNPRDFIDC FLIKMEQEKD NQKSEFNIEN LVGTVADLFV AGTETTSTTL RYGLLLLLKH PEVTAKVQEE IDHVIGRHRS PCMQDRSHMP YTDAVVHEIQ RYSDLVPTGV PHAVTTDTKF RNYLIPKGTT IMALLTSVLH DDKEFPNPNI FDPGHFLDKN GNFKKSDYFM PFSAGKRICA GEGLARMELF LFLTTILQNF NLKSVDDLKN LNTTAVTKGI VSLPPSYQIC FIPV
OMIM
601129
3D Structure
ModBase 3D Structure for P10632
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CYP2C8 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CYP2C8 recombinant protein
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
NCBI/Uniprot data below describe general gene information for CYP2C8. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,358 Da
NCBI Official Full Name
cytochrome P450 2C8 isoform a
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily C member 8
NCBI Official Symbol
CYP2C8  [Similar Products]
NCBI Official Synonym Symbols
CPC8; CYPIIC8; MP-12/MP-20
  [Similar Products]
NCBI Protein Information
cytochrome P450 2C8
UniProt Protein Name
Cytochrome P450 2C8
UniProt Synonym Protein Names
CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase
Protein Family
UniProt Gene Name
CYP2C8  [Similar Products]
NCBI Summary for CYP2C8
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
UniProt Comments for CYP2C8
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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