• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CYP4F2 recombinant protein :: Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2) Recombinant Protein

Scan QR to view Datasheet
Catalog # MBS948523
Unit / Price
Scan QR to view Datasheet
  0.05 mg (E-Coli)  /  $940 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $990 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,225 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $1,260 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,385 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,465 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,530 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,775 +2 FREE 8GB USB
  1 mg (E-Coli)  /  $2,100 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,300 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,370 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,425 +3 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,545 +4 FREE 8GB USB
CYP4F2 recombinant protein
Product Name

Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2), Recombinant Protein

Full Product Name

Recombinant Human Leukotriene-B (4) omega-hydroxylase 1 (CYP4F2)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
5-520aa, Full Length of Mature Protein
Sequence
SLSWLGLWPV AASPWLLLLL VGASWLLAHV LAWTYAFYDN CRRLRCFPQP PRRNWFWGHQ GMVNPTEEGM RVLTQLVATY PQGFKVWMGP ISPLLSLCHP DIIRSVINAS AAIAPKDKFF YSFLEPWLGD GLLLSAGDKW SRHRRMLTPA FHFNILKPYM KIFNESVNIM HAKWQLLASE GSACLDMFEH ISLMTLDSLQ KCVFSFDSHC QEKPSEYIAA ILELSALVSK RHHEILLHID FLYYLTPDGQ RFRRACRLVH DFTDAVIQER RRTLPSQGVD DFLQAKAKSK TLDFIDVLLL SKDEDGKKLS DEDIRAEADT FMFEGHDTTA SGLSWVLYHL AKHPEYQERC RQEVQELLKD REPKEIEWDD LAHLPFLTMC MKESLRLHPP VPVISRHVTQ DIVLPDGRVI PKGIICLISV FGTHHNPAVW PDPEVYDPFR FDPENIKERS PLAFIPFSAG PRNCIGQTFA MAEMKVVLAL TLLRFRVLPD HTEPRRKPEL VLRAEGGLWL RVEPLS
OMIM
122700
3D Structure
ModBase 3D Structure for P78329
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of CYP4F2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
CYP4F2 recombinant protein
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away.
NCBI/Uniprot data below describe general gene information for CYP4F2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,709 Da
NCBI Official Full Name
phylloquinone omega-hydroxylase CYP4F2
NCBI Official Synonym Full Names
cytochrome P450 family 4 subfamily F member 2
NCBI Official Symbol
CYP4F2  [Similar Products]
NCBI Official Synonym Symbols
NCBI Protein Information
phylloquinone omega-hydroxylase CYP4F2
UniProt Protein Name
Phylloquinone omega-hydroxylase CYP4F2
UniProt Synonym Protein Names
20-hydroxyeicosatetraenoic acid synthase
UniProt Gene Name
CYP4F2  [Similar Products]
UniProt Synonym Gene Names
20-HETE synthase  [Similar Products]
NCBI Summary for CYP4F2
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008]
UniProt Comments for CYP4F2
Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B4 omega-hydroxylase by mediating conversion of leukotriene-B4 (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B4 (20-OH LTB4) (PubMed:8026587, PubMed:9799565).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000