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anti-CYP51A1 antibody :: Rabbit anti-Human Cytochrome P450 51A1 Antibody

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Catalog # MBS003678
Unit / Price
  0.05 mL  /  $270 +1 FREE 8GB USB
  0.1 mL  /  $445 +1 FREE 8GB USB
anti-CYP51A1 antibody
Product Name

Cytochrome P450 51A1 (CYP51A1), Antibody

Also Known As

Rabbit Cytochrome P450 51A1 Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
509
Chromosome Location
Chromosome: 7; NC_000007.13 (91741463..91764059, complement). Location: 7q21.2
OMIM
601637
3D Structure
ModBase 3D Structure for Q16850
Host
Rabbit
Species Reactivity
Human
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Concentration
1 mg/ml (lot specific)
Other Notes
Small volumes of anti-CYP51A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CYP51A1 antibody
ELISA (EIA), Western Blot (WB)
NCBI/Uniprot data below describe general gene information for CYP51A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,806 Da[Similar Products]
NCBI Official Full Name
lanosterol 14-alpha demethylase isoform 1
NCBI Official Synonym Full Names
cytochrome P450, family 51, subfamily A, polypeptide 1
NCBI Official Symbol
CYP51A1  [Similar Products]
NCBI Official Synonym Symbols
LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM
  [Similar Products]
NCBI Protein Information
lanosterol 14-alpha demethylase; CYPLI; cytochrome P450LI; cytochrome P45014DM; cytochrome P450 51A1; cytochrome P450-14DM; lanosterol 14-alpha-demethylase; cytochrome P450, 51 (lanosterol 14-alpha-demethylase)
UniProt Protein Name
Lanosterol 14-alpha demethylase
UniProt Synonym Protein Names
CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Sterol 14-alpha demethylase
UniProt Gene Name
CYP51A1  [Similar Products]
UniProt Synonym Gene Names
CYP51; LDM  [Similar Products]
UniProt Entry Name
CP51A_HUMAN
NCBI Summary for CYP51A1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for CYP51A1
CYP51A1: Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 1.14.13.70; Lipid Metabolism - steroid biosynthesis; Oxidoreductase

Chromosomal Location of Human Ortholog: 7q21.2

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: sterol 14-demethylase activity; iron ion binding; heme binding

Biological Process: xenobiotic metabolic process; sterol metabolic process; cholesterol biosynthetic process; steroid biosynthetic process; cholesterol biosynthetic process via 24,25-dihydrolanosterol
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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