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CYP51A1 elisa kit :: Human cytochrome P450, family 51, subfamily A, polypeptide 1 ELISA Kit

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Catalog # MBS9341895
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CYP51A1 elisa kit
Product Name

cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1), ELISA Kit

Full Product Name

Human Lanosterol 14-alpha demethylase, CYP51A1 ELISA Kit

Product Synonym Names
Human Lanosterol 14-alpha demethylase (CYP51A1) ELISA kit; CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1; cytochrome P450; 51 (lanosterol 14-alpha-demethylase) ; lanosterol 14-alpha-demethylase; sterol 14-alpha demethylase; cytochrome P450; family 51; subfamily A; polypeptide 1
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
601637
3D Structure
ModBase 3D Structure for Q16850
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of CYP51A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CYP51A1purchase
MBS9341895 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYP51A1. The ELISA analytical biochemical technique of the MBS9341895 kit is based on CYP51A1 antibody-CYP51A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP51A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP51A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for CYP51A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
56,806 Da
NCBI Official Full Name
lanosterol 14-alpha demethylase isoform 1
NCBI Official Synonym Full Names
cytochrome P450, family 51, subfamily A, polypeptide 1
NCBI Official Symbol
CYP51A1  [Similar Products]
NCBI Official Synonym Symbols
LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM
  [Similar Products]
NCBI Protein Information
lanosterol 14-alpha demethylase; CYPLI; cytochrome P450LI; cytochrome P45014DM; cytochrome P450 51A1; cytochrome P450-14DM; lanosterol 14-alpha-demethylase; cytochrome P450, 51 (lanosterol 14-alpha-demethylase)
UniProt Protein Name
Lanosterol 14-alpha demethylase
UniProt Synonym Protein Names
CYPLI; Cytochrome P450 51A1; Cytochrome P450-14DM; Cytochrome P45014DM; Cytochrome P450LI; Sterol 14-alpha demethylase
UniProt Gene Name
CYP51A1  [Similar Products]
UniProt Synonym Gene Names
CYP51; LDM; Cytochrome P45014DM  [Similar Products]
UniProt Entry Name
CP51A_HUMAN
NCBI Summary for CYP51A1
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
UniProt Comments for CYP51A1
CYP51A1: Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - steroid biosynthesis; EC 1.14.13.70; Oxidoreductase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 7q21.2

Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane

Molecular Function: sterol 14-demethylase activity; iron ion binding; heme binding

Biological Process: xenobiotic metabolic process; cholesterol biosynthetic process; sterol metabolic process; steroid biosynthetic process; cholesterol biosynthetic process via 24,25-dihydrolanosterol
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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