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anti-ISL2 antibody :: Mouse anti-Human ISL2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS120461
Unit / Price
0.1 mg  /  $345 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ISL2, Monoclonal Antibody

 Also Known As   

Mouse monoclonal antibody Anti-Human ISL2

 Product Synonym Names    Homo sapiens ISL LIM homeobox 2, mRNA (cDNA clone MGC:9275 IMAGE:3866562), complete cds.
 Product Gene Name   

anti-ISL2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609481
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    203C5a
 Host    Mouse
 Species Reactivity    Human
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 Concentration    100 ug/ml (1.0 ml) (lot specific)
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 Preparation    This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
 Sterility    Filtered through a 0.22 um membrane.
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 Other Notes    Small volumes of anti-ISL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ISL2 antibody

   Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways By similarity.[UniProtKB Function]
 Applications Tested/Suitable for anti-ISL2 antibody   

Dot Blot (DB), Immunocytochemistry (ICC)

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 Quality Control of anti-ISL2 antibody    Western blot analysis of immunized recombinant protein, using anti-ISL2 monoclonal antibody.
anti-ISL2 antibody Quality Control image
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 Quality Control #2 of anti-ISL2 antibody    Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-ISL2 antibody Quality Control #2 image
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 Immunocytochemistry (ICC) of anti-ISL2 antibody    Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-ISL2 mAb. [Lot No.203C5a-1]
anti-ISL2 antibody Immunocytochemistry (ICC) (ICC) image
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NCBI/Uniprot data below describe general gene information for ISL2. It may not necessarily be applicable to this product.
 NCBI GI #    15080437
 NCBI GeneID    64843
 NCBI Accession #    BC011967 [Other Products]
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 UniProt Secondary Accession #    B3KM37 [Other Products]
 UniProt Related Accession #    Q96A47 [Other Products]
 Molecular Weight    39,768 Da
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 NCBI Official Full Name    Homo sapiens ISL LIM homeobox 2, mRNA
 NCBI Official Synonym Full Names    ISL LIM homeobox 2
 NCBI Official Symbol    ISL2 [Similar Products]
 NCBI Protein Information    insulin gene enhancer protein ISL-2; ISL2 transcription factor, LIM/homeodomain, (islet-2)
 UniProt Protein Name    Insulin gene enhancer protein ISL-2
 Protein Family    Insulin gene enhancer protein
 UniProt Gene Name    ISL2 [Similar Products]
 UniProt Entry Name    ISL2_HUMAN
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 UniProt Comments for ISL2    islet-2: Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: nucleus

Molecular Function: DNA binding; zinc ion binding; sequence-specific DNA binding

Biological Process: peripheral nervous system neuron development; negative regulation of neuron differentiation; visceral motor neuron differentiation; regulation of transcription, DNA-dependent; spinal cord motor neuron cell fate specification; neuron development; retinal ganglion cell axon guidance
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 Research Articles on ISL2    1. Experiments in Isl2/EphA3 knock-in mice test the interactions between effects of molecular labels and correlated activity during the development of neural connectivity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ISL2 antibodyDiseases associated with anti-ISL2 antibody
 Reference Product  PubMed Publications
 ISL1 antibody  >14 publications with ISL2 and ISL1
 LHX3 antibody  >6 publications with ISL2 and LHX3
 LDB1 antibody  >4 publications with ISL2 and LDB1
 EPHB1 antibody  >2 publications with ISL2 and EPHB1
 NEUROG2 antibody  >1 publications with ISL2 and NEUROG2
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >1 publications with ISL2 and Hepatitis
 Nervous System Diseases Antibodies  >1 publications with ISL2 and Nervous System Diseases
 Learning Disorders Antibodies  >1 publications with ISL2 and Learning Disorders
 Inflammation Antibodies  >1 publications with ISL2 and Inflammation
Organs/Tissues associated with anti-ISL2 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >13 publications with ISL2 and Embryonic Tissue
 Eye Antibodies  >12 publications with ISL2 and Eye
 Brain Antibodies  >10 publications with ISL2 and Brain
 Intestine Antibodies  >1 publications with ISL2 and Intestine
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