P40136.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
92,478 Da
NCBI Official Full Name
Calmodulin-sensitive adenylate cyclase
NCBI Protein Information
calmodulin-sensitive adenylate cyclase
UniProt Protein Name
Calmodulin-sensitive adenylate cyclase
UniProt Synonym Protein Names
ATP pyrophosphate-lyase; Adenylyl cyclase; Anthrax edema toxin adenylate cyclase component; Edema factor; EF
UniProt Synonym Gene Names
UniProt Entry Name
CYAA_BACAN
UniProt Comments for pxo1_122
One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. EF is a calmodulin-dependent adenylyl cyclase that, when associated with PA, causes edema. EF is not toxic by itself and it is required for the survival of germinated spores within macrophages at the early stages of infection. Provokes dramatic elevation of intracellular cAMP levels in the host.
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Products associated with pxo1_122 blocking peptide
Pathways associated with pxo1_122 blocking peptide
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