NP_001313.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cystatin-SA
NCBI Official Synonym Full Names
cystatin SA
NCBI Protein Information
cystatin-SA; cystatin 2; cystatin-2; cystatin S5; cystatin-S5; cysteine-proteinase inhibitor; salivary cysteine (thiol) protease inhibitor
UniProt Protein Name
Cystatin-SA
UniProt Synonym Protein Names
Cystatin-2; Cystatin-S5
UniProt Entry Name
CYTT_HUMAN
NCBI Summary for CST2
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma. [provided by RefSeq, Jul 2008]
UniProt Comments for CST2
CST2: Thiol protease inhibitor. Belongs to the cystatin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 20p11.21
Cellular Component: extracellular space
Molecular Function: cysteine protease inhibitor activity
Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste
Research Articles on CST2
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Pathways associated with CST2 recombinant protein
Organs/Tissues associated with CST2 recombinant protein
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