AAB06463.1
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,006 Da
NCBI Official Full Name
fibroblast growth factor 5
NCBI Official Synonym Full Names
fibroblast growth factor 5
NCBI Protein Information
fibroblast growth factor 5
UniProt Protein Name
Fibroblast growth factor 5
UniProt Synonym Protein Names
Heparin-binding growth factor 5; HBGF-5; Smag-82
UniProt Synonym Gene Names
NCBI Summary for FGF5
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
UniProt Comments for FGF5
Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase ().
Research Articles on FGF5
Precautions
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Disclaimer
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Products associated with FGF5 antibody pair kit
Pathways associated with FGF5 antibody pair kit
Diseases associated with FGF5 antibody pair kit
Organs/Tissues associated with FGF5 antibody pair kit
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