NP_001271173.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,047 Da
NCBI Official Full Name
prepronociceptin isoform 2
NCBI Official Synonym Full Names
prepronociceptin
NCBI Official Synonym Symbols
NOP; OFQ; N/OFQ; PPNOC; ppN/OFQ [Similar Products]
NCBI Protein Information
prepronociceptin
UniProt Protein Name
Prepronociceptin
UniProt Synonym Protein Names
NocistatinNociceptinAlternative name(s):Orphanin FQ; PPNOC
UniProt Synonym Gene Names
NCBI Summary for PNOC
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin. [provided by RefSeq, Jul 2015]
UniProt Comments for PNOC
Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
Research Articles on PNOC
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Products associated with PNOC antibody pair kit
Pathways associated with PNOC antibody pair kit
Diseases associated with PNOC antibody pair kit
Organs/Tissues associated with PNOC antibody pair kit
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